Host organisms utilise a range of genetically encoded cell death programmes in response to
pathogen challenge. Host cell death can restrict pathogen proliferation by depleting their …

The last years have seen a steady increase in our understanding of legumain biology that is
driven from two largely uncoupled research arenas, the mammalian and the plant legumain …

INTRODUCTION Cellular damage caused by wounding triggers signals to alert the
surrounding tissue. As a universal process in all multicellular organisms, these signals …

Stress granules (SGs) are highly conserved cytoplasmic condensates that assemble in
response to stress and contribute to maintaining protein homeostasis. These membraneless …

The cysteine protease legumain plays important functions in immunity and cancer at
different cellular locations, some of which appeared conflicting with its proteolytic activity and …

Apoptosis and other types of regulated cell death have been defined as fundamental
processes in plant and animal development, but the occurrence of, and possible roles for …

Autophagy is a major nutrient recycling mechanism in plants. However, its functional
connection with programmed cell death (PCD) is a topic of active debate and remains not …

Cell death of xylem elements is manifested by rupture of the tonoplast and subsequent
autolysis of the cellular contents. Metacaspases have been implicated in various forms of …

Metacaspases are distant relatives of the metazoan caspases, found in plants, fungi, and
protists. However, in contrast with caspases, information about the physiological substrates …

Plant metacaspases mediate programmed cell death in development, biotic and abiotic
stresses, damage-induced immune response, and resistance to pathogen attack. Most …