Conventional drug administration usually faces the problems of degradation and rapid
excretion when crossing many biological barriers, leading to only a small amount of drugs …

The first microfluidic microphysiological systems (MPS) entered the academic scene more
than 15 years ago and were considered an enabling technology to human in vitro (patho) …

Recent FDA modernization act 2.0 has led to increasing industrial R&D investment in
advanced in vitro 3D models such as organoids, spheroids, organ-on-chips, 3D bioprinting …

Identification and approval of new drugs for use in patients requires extensive preclinical
studies and clinical trials. Preclinical studies rely on in vitro experiments and animal models …

Reliable in vitro models with human-derived cells that recapitulate in vivo-like physiologies
are required for drug discovery and development to reduce the gap between the results of …

Cardiometabolic diseases and cancer are among the most common diseases worldwide
and are a serious concern to the healthcare system. These conditions, apparently distant …

Osteoporosis, characterized by low bone density and increased risk of fractures, represents
a major healthcare challenge. Anti-resorptive and anabolic medications are now used to …

Transwell-based airway models have become increasingly important to study the effects of
respiratory diseases and drug treatment at the air-liquid interface of the lung epithelial …