Wound healing is an intricate process that requires complex coordination between many cell
types and an appropriate extracellular microenvironment. Chronic wounds often suffer from …

Current advances in novel drug delivery systems (DDSs) to release growth factors (GFs)
represent a great opportunity to develop new therapies or enhance the effectiveness of …

Colostrum is a nutritious milk synthesized by mammals during the postpartum period, and its
rich bioactive components has led to a global increase in the consumption of bovine …

Background Foot ulcers are a major complication of diabetes mellitus, often leading to
amputation. Growth factors derived from blood platelets, endothelium, or macrophages …

Diabetes mellitus (DM) induced wound healing impairment remains a serious health
problem and burden on the clinical obligation for high amputation rates. Based on the …

Recurrence rates of diabetic foot ulcers vary widely in the published literature. The aim of
this systematic review is to estimate recurrence rates of diabetic foot ulcers. We did a …

Chemotaxis, mitogenesis, motogenesis and cytoprotection are common cellular events
involved in both tumourigenesis and tissue repair, which appear amplified upon growth …

The rise in lower extremity amputations due to nonhealing of foot ulcers in diabetic patients
calls for rapid improvement in effective treatment regimens. Administration of growth factors …

Management of diabetic foot ulcers remains a rather challenging task. Epidermal growth
factor (EGF) plays a central role in wound healing. It acts on epithelial cells and fibroblasts …

Diabetic foot ulcer is a principal diabetic complication. It has been shown that diabetic
patients have decreased growth factor concentrations in their tissues, particularly epidermal …