The recognition and management of life-threatening hemorrhage in the polytrauma patient
poses several challenges to prehospital rescue personnel and hospital providers. First …

Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …

BACKGROUND The use of massive transfusion protocols (MTPs) in the resuscitation of
hemorrhaging trauma patients ensures rapid delivery of blood products to improve …

Background The efficacies of fresh frozen plasma and coagulation factor transfusion have
been widely evaluated in trauma-induced coagulopathy management during the acute post …

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BACKGROUND: Fibrinogen is the first coagulation factor to decrease after massive
hemorrhage. European massive transfusion guidelines recommend early repletion of …

Background Fibrinogen plays an important role in haemostasis during the early phase of
trauma, and low fibrinogen levels after severe trauma are associated with haemostatic …

Trauma induces a change in nearly every observable aspect of hemostasis, generally
tipping the balance toward trauma-induced coagulopathy (TIC) and bleeding in the critical …

Aim The shock index has been suggested as a screening tool for predicting postpartum
hemorrhage (PPH); however, there is little comprehensive evidence regarding its predictive …

Aims Point-of-care viscoelastic tests such as rotational thrombelastometry (ROTEM) and
thromboelastography (TEG) give rapid information on the kinetics of clot formation, clot …