The development of sodium-glucose transporter 2 inhibitor (SGLT2i) broadens the
therapeutic strategies in treating diabetes mellitus. By inhibiting sodium and glucose …

Emerging evidence indicates that obesity, even in the absence of diabetes, contributes
significantly to the development and progression of chronic kidney disease (CKD) …

Diabetic neuropathy (DN) is a complicated inauspicious outcome of diabetes, like other
abnormalities of diabetes the cause of DN is still vague and it may be the result of various …

The aim of present study is to investigate the role of 6-gingerol in ameliorating the renal
injury in streptozotocin (STZ)-induced diabetic rats. The diabetes was induced by using a …

Objectives Literature findings have instituted the role of hyperglycemia-induced oxidative
stress and inflammation in the pathogenesis of cognitive derangement in diabetes mellitus …

Adequate 24-h BP control presently offers the most feasible intervention for reducing
glomerular BP transmission and improving suboptimal outcomes in CKD. Investigations …

Abstract Background/Aim: We examined the influence of chronic treatment with angiotensin-
(1–7)[Ang-(1–7)] on renox (renal NADPH oxidase, NOX-4) and the development of renal …

Aims/hypothesis In diabetes, advanced glycation end-products (AGEs) and the AGE
precursor methylglyoxal (MGO) are associated with endothelial dysfunction and the …

Acute subcutaneous administration of Angiotensin II (Ang II) causes a rise in blood pressure
in diabetic Wistar rats. Diabetes was induced using streptozotocin (70 mg/kg, iv). Chronic …

Omega-3 polyunsaturated fatty acids (n-3 PUFA) show beneficial effects in cardiovascular
disease, IgA, and diabetic nephropathy; however, the mechanisms underlying these benefits …