Necroptosis is a genetically regulated form of necrotic cell death that has emerged as an
important pathway in human disease. The necroptosis pathway is induced by a variety of …

The process of programmed cell death, or apoptosis, is generally characterized by distinct
morphological characteristics and energy-dependent biochemical mechanisms. Apoptosis is …

Posttranslational modifications (PTMs) of proteins, the major mechanism of protein function
regulation, play important roles in regulating a variety of cellular physiological and …

Reactive oxygen or nitrogen species (ROS/RNS) generated endogenously or in response to
environmental stress have long been implicated in tissue injury in the context of a variety of …

Preeclampsia is a major contributor to the maternal and neonatal mortality and morbidity. 1,
2 It is the 2nd largest cause of maternal mortality worldwide and affects 5% to 7% of …

Cell death is discriminated into two main forms: apoptosis and necrosis. In contrast to
necrosis, apoptosis is a regulated, energy-dependent form of cell death leading to …

The complex functions of the liver in biosynthesis, metabolism, clearance, and host defense
are tightly dependent on an adequate microcirculation. To guarantee hepatic homeostasis …

For a long time necrosis was considered as an alternative to programmed cell death,
apoptosis. Indeed, necrosis has distinct morphological features and it is accompanied by …

Apoptosis is an evolutionarily conserved sequential process of cell death to maintain a
homeostatic balance between cell formation and cell death. It is a vital process for normal …

Necrosis has long been described as a consequence of physico-chemical stress and thus
accidental and uncontrolled. Recently, it is becoming clear that necrotic cell death is as well …