The Multifaceted Effects of Non-Steroidal and Non-Opioid Anti-Inflammatory and Analgesic Drugs on Platelets: Current Knowledge, Limitations, and Future …

A Tsoupras, DA Gkika, I Siadimas… - Pharmaceuticals, 2024 - mdpi.com
Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely utilized
pharmaceuticals worldwide. Besides their recognized anti-inflammatory effects, these drugs …

[HTML][HTML] Impairment of aspirin antiplatelet effects by non-opioid analgesic medication

A Polzin, T Hohlfeld, M Kelm, T Zeus - World Journal of Cardiology, 2015 - ncbi.nlm.nih.gov
Aspirin is the mainstay in prophylaxis of cardiovascular diseases. Impaired aspirin
antiplatelet effects are associated with enhanced incidence of cardiovascular events …

Quantification of adherent platelets on polymer-based biomaterials. Comparison of colorimetric and microscopic assessment

S Braune, S Zhou, B Groth… - Clinical hemorheology and …, 2015 - content.iospress.com
BACKGROUND: Platelet adhesion to artificial surfaces is one of the most important
indicators for the thrombogenicity of implant materials. Currently, a variety of enzyme activity …

Intake of aspirin prior to metamizole does not completely prevent high on treatment platelet reactivity

C Pfrepper, C Dietze, Y Remane, T Bertsche… - European Journal of …, 2020 - Springer
Purpose Metamizole can sterically inhibit aspirin (ASA) from binding to cyclooxygenase 1
(COX1). It is recommended that ASA should be taken 30 min prior to metamizole to maintain …

[HTML][HTML] Role of dipyrone in the high on-treatment platelet reactivity amongst acetylsalicylic acid-treated patients undergoing peripheral artery revascularisation

J Hartinger, R Novotny, J Bilkova, T Kvasnicka… - Medical Principles and …, 2018 - karger.com
Objective: To evaluate the effects of dipyrone on sensitivity to aspirin (acetylsalicylic acid
[ASA]) in patients who underwent peripheral artery vascular reconstruction. Subjects and …

Metamizole and platelet inhibition by Aspirin following on-pump coronary artery bypass grafting

M Wilczyński, MT Wybraniec, M Sanak, J Góral… - … of Cardiothoracic and …, 2018 - Elsevier
Objective The purpose of the study was to evaluate the impact of intravenous metamizole on
platelet inhibition by aspirin in patients with coronary artery disease early after on-pump …

Dynamic in vitro hemocompatibility testing of poly (ether imide) membranes functionalized with linear, methylated oligoglycerol and oligo (ethylene glycol)

S Braune, M von Ruesten-Lange… - Clinical …, 2013 - content.iospress.com
Linear, side-chain methylated oligoglycerols (OGMe) were recently reported as potential
surface passivating molecules for improving the protein resistance of cardiovascular …

Metamizole inhibits arachidonic acid-induced platelet aggregation after surgery and impairs the effect of aspirin in hospitalized patients

C Pfrepper, S Deters, M Metze, R Siegemund… - European Journal of …, 2019 - Springer
Purpose The inhibitory effect of metamizole on platelet aggregation is known for several
years, but most studies were conducted in healthy volunteers with contradictory results …

Potential drug-drug interactions and their associated factors in hospitalized COVID-19 patients with comorbidities

ID Rahmadani, S Irawati, YI Wibowo, AP Setiadi - PeerJ, 2023 - peerj.com
Background Hospitalized COVID-19 patients with comorbidities receive more complex drug
therapy. This increases the probability of potential drug-drug interactions (pDDIs). Studies …

Impact of analgesic regimen on patient outcome following subarachnoid hemorrhage: positive adjuvant effects of metamizole

P Solar, M Joukal, C Silar… - British Journal of …, 2022 - Taylor & Francis
Introduction Various analgesics are used to control intense headaches in patients following
subarachnoid hemorrhage. In addition to pain control, it has been shown that some …