Antimalarial drug resistance: an overview

HA Antony, SC Parija - Tropical parasitology, 2016 - journals.lww.com
Malaria is a major public health burden throughout the world. Resistance to the antimalarial
drugs has increased the mortality and morbidity rate that is achieved so far through the …

New developments in Plasmodium vivax malaria: severe disease and the rise of chloroquine resistance

RN Price, NM Douglas, NM Anstey - Current opinion in infectious …, 2009 - journals.lww.com
New developments in Plasmodium vivax malaria: severe disease... : Current Opinion in
Infectious Diseases New developments in Plasmodium vivax malaria: severe disease and the …

[HTML][HTML] The molecular basis of antimalarial drug resistance in Plasmodium vivax

LE Buyon, B Elsworth, MT Duraisingh - International Journal for …, 2021 - Elsevier
Plasmodium vivax is the most geographically widespread cause of human malaria and is
responsible for the majority of cases outside of the African continent. While great progress …

[HTML][HTML] Diagnosis and treatment of Plasmodium vivax malaria

JK Baird, N Valecha, S Duparc, NJ White… - The American journal …, 2016 - ncbi.nlm.nih.gov
The diagnosis and treatment of Plasmodium vivax malaria differs from that of Plasmodium
falciparum malaria in fundamentally important ways. This article reviews the guiding …

Genomic analysis of Plasmodium vivax describes patterns of connectivity and putative drivers of adaptation in Ethiopia

AM Kebede, E Sutanto, H Trimarsanto… - Scientific Reports, 2023 - nature.com
Ethiopia has the greatest burden of Plasmodium vivax in Africa, but little is known about the
epidemiological landscape of parasites across the country. We analysed the genomic …

Return of chloroquine-sensitive Plasmodium falciparum parasites and emergence of chloroquine-resistant Plasmodium vivax in Ethiopia

SK Mekonnen, A Aseffa, N Berhe, T Teklehaymanot… - Malaria journal, 2014 - Springer
Abstract Background Increased resistance by Plasmodium falciparum parasites led to the
withdrawal of the antimalarial drugs chloroquine and sulphadoxine-pyrimethamine in …

Drug resistance of Plasmodium falciparum and Plasmodium vivax isolates in Indonesia

FV Rahmasari, PBS Asih, FK Dewayanti… - Malaria Journal, 2022 - Springer
This review article aims to investigate the genotypic profiles of Plasmodium falciparum and
Plasmodium vivax isolates collected across a wide geographic region and their association …

Implementing parasite genotyping into national surveillance frameworks: feedback from control programmes and researchers in the Asia–Pacific region

R Noviyanti, O Miotto, A Barry, J Marfurt, S Siegel… - 2020 - Springer
Abstract The Asia–Pacific region faces formidable challenges in achieving malaria
elimination by the proposed target in 2030. Molecular surveillance of Plasmodium parasites …

Phenotypic and genotypic characterisation of drug-resistant Plasmodium vivax

RN Price, S Auburn, J Marfurt, Q Cheng - Trends in parasitology, 2012 - cell.com
In this review we present recent developments in the analysis of Plasmodium vivax clinical
trials and ex vivo drug-susceptibility assays, as well approaches currently being used to …

Integrative Genetic Manipulation of Plasmodium cynomolgi Reveals Multidrug Resistance-1 Y976F Associated With Increased In Vitro Susceptibility to Mefloquine

KE Ward, P Christensen, A Racklyeft… - The Journal of …, 2023 - academic.oup.com
The lack of a long-term in vitro culture method has severely restricted the study of
Plasmodium vivax, in part because it limits genetic manipulation and reverse genetics. We …