Cardiovascular disease and thrombosis in HIV infection

MV Perkins, SB Joseph, DP Dittmer… - … , and vascular biology, 2023 - Am Heart Assoc
HIV infection has transitioned from an acute, fatal disease to a chronic one managed by
antiretroviral therapy. Thus, the aging population of people living with HIV (PLWH) continues …

[HTML][HTML] Platelet and HIV Interactions and Their Contribution to Non-AIDS Comorbidities

T Awamura, ES Nakasone, LM Gangcuangco… - Biomolecules, 2023 - mdpi.com
Platelets are anucleate cytoplasmic cell fragments that circulate in the blood, where they are
involved in regulating hemostasis. Beyond their normal physiologic role, platelets have …

Risk factors and prognosis of thrombocytopenia in people living with HIV/AIDS

X Lv, P Li, P Yue, P Tang… - Therapeutic Advances in …, 2023 - journals.sagepub.com
Background: Thrombocytopenia is a common hematological manifestation in people living
with human immunodeficiency virus (HIV) or acquired immune deficiency syndrome (AIDS; …

[HTML][HTML] EcoHIV-Infected Mice Show No Signs of Platelet Activation

HR Alfar, DN Nthenge-Ngumbau, KE Saatman… - Viruses, 2023 - mdpi.com
Platelets express several surface receptors that could interact with different viruses. To
understand the mechanisms of HIV-1′ s interaction with platelets, we chose the EcoHIV …

[HTML][HTML] The prevalence of thrombocytopenia and leucopenia among people living with HIV/AIDS in Ethiopia: a systematic review and meta-analysis

H Bisetegn, H Ebrahim - PLoS One, 2021 - journals.plos.org
Introduction Thrombocytopenia and leucopenia are frequently encountered hematological
disorders among people living with HIV/AIDS. This systematic review and meta-analysis …

Coagulation Parameters in Human Immunodeficiency Virus Infected Patients: A Systematic Review and Meta‐Analysis

S Getawa, T Adane - AIDS Research and Treatment, 2022 - Wiley Online Library
Background. Coagulation abnormalities are common complications of human
immunodeficiency virus (HIV) infection. Highly active antiretroviral treatment (HAART) …

[HTML][HTML] Regulation of megakaryo/thrombopoiesis by endosomal toll-like receptor 7 and 8 activation of CD34+ cells in a viral infection model

CS Rodríguez, N Charó, S Tatti, RM Gómez… - Research and Practice …, 2023 - Elsevier
Abstract Background CD34+ cells, megakaryocytes (MKs), and platelets express toll-like
receptors (TLRs) that enable these cells to amplify the host innate immune response …

Increased platelet–CD8+ T-cell aggregates displaying high activation, exhaustion, and tendency to death correlate with disease progression in people with HIV-1

F Wu, Y Li, N Jiang, X Jiang, X Liu… - Journal of Leukocyte …, 2024 - academic.oup.com
Platelets engage in HIV-1 infection by interacting with immune cells, which has been
realized broadly. However, the potential interaction between platelets and CD8+ T cells …

Prevalence and predictors of cytopenias in HIV-infected adults at initiation of antiretroviral therapy in Mehal Meda hospital, Central Ethiopia

T Fiseha, H Ebrahim - Journal of Blood Medicine, 2022 - Taylor & Francis
Background Hematologic abnormalities are common complications of patients infected with
HIV associated with accelerated deterioration in CD4+ cell counts, disease progression …

Immuno-haematological abnormalities of HIV-infected patients before and after initiation of highly active antiretroviral therapy in the antiretroviral therapy clinics of six …

M Tilahun, A Gedefie, E Ebrahim, A Seid… - Journal of Blood …, 2022 - Taylor & Francis
Background In people living with the human immunodeficiency virus, haematological
abnormalities have been linked to an increased risk of disease progression and mortality …