Cutaneous melanoma is a highly immunogenic malignancy that is surgically curable at early
stages but life-threatening when metastatic. Here we integrate high-plex imaging, 3D high …

To better understand intrinsic resistance to immune checkpoint blockade (ICB), we
established a comprehensive view of the cellular architecture of the treatment-naive …

Recent developments in single-cell multi-omics technologies have provided the ability to
identify diverse cell types and decipher key components of the tumor microenvironment …

Immune checkpoint therapies have significantly advanced cancer treatment. Nevertheless,
the high costs and potential adverse effects associated with these therapies highlight the …

Background Numerous meta-analyses and clinical studies have shown that subtypes of
immune cells are associated with the development of skin cancer, but it is not clear whether …

Cutaneous melanoma is the deadliest form of skin cancer. Despite advancements in
treatment, many patients still face poor outcomes. A deeper understanding of the …

Melanoma is a lethal skin disease that develops from moles. This study aimed to integrate
multimodal data to predict metastatic melanoma, which is highly aggressive and difficult to …

Melanoma is a relatively rare disease worldwide; nevertheless, it has a great relevance in
some countries, such as in Europe. In order to shed some light upon the transcriptional …

Melanoma is a relative rare disease worldwide, nevertheless it has a great relevance in
some countries such as in Europe. In order to shed some light upon the transcriptional …