Objectives We performed a systematic review and meta-analysis of all the available
evidence to assess the efficacy and safety of paracetamol for the treatment of patent ductus …

The ductus arteriosus (DA) is a fetal shunt vessel that, during prenatal life, diverts blood
away from the pulmonary circulation into the systemic circulation toward the placenta …

Objective To compare the efficacy of enteral paracetamol and intravenous indomethacin for
closure of patent ductus arteriosus (PDA) in preterm neonates. Design Randomized …

Background Patent ductus arteriosus (PDA) is one of most common complications in preterm
infants. Although ibuprofen represents the first choice for the closure of PDA, this treatment …

Increasing recent evidence favors paracetamol use for patent ductus arteriosus (PDA)
closure in preterms. Our study aims were (1) to assess efficacy and safety of intravenous (iv) …

Objective: To evaluate the literature describing acetaminophen use in treatment of patent
ductus arteriosus (PDA). Data Sources: Searches were conducted in MEDLINE with full text …

Paracetamol seems to have similar success rates compared with indomethacin and
ibuprofen in closing patent ductus arteriosus (PDA) in preterm infants, but with a better safety …

Introduction: Haemodynamically significant patent ductus arteriosus is a significant cause of
morbidity and mortality in pre-term infants. This retrospective study was conducted to …

Opinions are divided regarding the management of a persistently patent ductus arteriosus
(PDA). Some of the adverse effects associated with a large hemodynamically significant …

Background: Currently, the first line treatment of persistent ductus arteriosus (PDA) is either
indomethacin or ibuprofen. However, the potentially life-threatening side effects associated …