Size matters: ryanodine receptor cluster size heterogeneity potentiates calcium waves

Y Xie, Y Yang, S Galice, DM Bers, D Sato - Biophysical journal, 2019 - cell.com
Ryanodine receptors (RyRs) mediate calcium (Ca)-induced Ca release and intracellular Ca
homeostasis. In a cardiac myocyte, RyRs group into clusters of variable size from a few to …

Abnormal expression of miR-331 leads to impaired heart function

JJ Zhang, LP Wang, RC Li, M Wang, ZH Huang, M Zhu… - Science Bulletin, 2019 - Elsevier
MicroRNAs (miRNAs) play important roles in maintaining normal heart function. Abnormal
expression of miR-331 has been observed in the hearts of patients with atrial fibrillation and …

Let there be light: a bright future for Ca2+ signaling

G Ma, J Liu, NT Nguyen, Y Zhou, Y Wang - Science Bulletin, 2018 - ui.adsabs.harvard.edu
Abstract Calcium ion (Ca 2+) is a ubiquitous second messenger in eukaryotic cells. In
response to electrical, hormonal, or mechanical stimulation, cytosolic Ca 2+ levels increase …