In 2010, the Mediterranean diet was recognized by UNESCO as an Intangible Cultural
Heritage of Humanity. Olive oil is the most characteristic food of this diet due to its high …

To enable survival in adverse conditions, cancer cells undergo global metabolic
adaptations. The amino acid cysteine actively contributes to cancer metabolic remodelling …

Background Chronic illnesses like obesity, type 2 diabetes (T2D) and cardiovascular
diseases, are worldwide major causes of morbidity and mortality. These pathological …

DNA methylation is the most extensively studied mechanism of epigenetic gene regulation.
Increasing evidence indicates that DNA methylation is labile in response to nutritional and …

DNA methylation is an epigenetic mechanism that is essential for regulating gene
transcription. However, aberrant DNA methylation, which is a nearly universal finding in …

Nutritional factors play a life-long role in human health. Indeed, there is growing evidence
that one of the mechanisms by which nutrients and bioactive compounds affect metabolic …

During pregnancy and/or lactation, maternal nutrition is related to the adequate
development of the fetus, newborn and future adult, likely by modifications in fetal …

The placenta is a transient organ found in eutherian mammals that evolved primarily to
provide nutrients for the developing fetus. The placenta exchanges a wide array of nutrients …

The circadian clock system instructs 24-h rhythmicity on gene expression in essentially all
cells, including adipocytes, and epigenetic mechanisms may participate in this regulation …

Obesity is a worldwide epidemic responsible for 5% of global mortality. The risks of
developing other key metabolic disorders like diabetes, hypertension and cardiovascular …