Halimane diterpenoids: sources, structures, nomenclature and biological activities

AM Roncero, IE Tobal, RF Moro, D Díez… - Natural product …, 2018 - pubs.rsc.org
Covering: 1970 to 2017 Diterpenes with a halimane skeleton constitute a small group of
natural products that can be biogenetically considered as being between labdane and …

Dehydration reactions in polyfunctional natural products

P Hjerrild, T Tørring, TB Poulsen - Natural Product Reports, 2020 - pubs.rsc.org
Covering: up to 2020 In this review, we present state of the art methods for performing
dehydration reactions in alcohol substrates to deliver alkene products. The dehydration of …

Deacylative Homolysis of Ketone C(sp3)–C(sp2) Bonds: Streamlining Natural Product Transformations

M Šimek, S Mahato, BW Dehnert… - Journal of the American …, 2025 - ACS Publications
The homolytic cleavage of C–C bonds adjacent to specific functional groups has lately
emerged as a versatile approach for molecular diversification. Despite the ubiquity and …

Diterpenoids of terrestrial origin

JR Hanson - Natural Product Reports, 2011 - pubs.rsc.org
Covering: January 2009 to December 2010 This review covers the isolation and chemistry of
diterpenoids from terrestrial as opposed to marine sources and includes labdanes …

Total syntheses of Sesterterpenoid ansellones A and B, and Phorbadione

W Zhang, H Yao, J Yu, Z Zhang, R Tong - Angewandte Chemie, 2017 - Wiley Online Library
Ansellane‐type sesterterpenoids including, ansellones A‐G and (+)‐phorbadione are
structurally novel marine secondary metabolites which exhibit anticancer and anti‐HIV …

Synthesis and bio-inspired optimization of drimenal: Discovery of chiral drimane fused oxazinones as promising antifungal and antibacterial candidates

D Li, S Zhang, Z Song, W Li, F Zhu, J Zhang… - European journal of …, 2018 - Elsevier
The synthesis of antifungal natural product drimenal was accomplished. Bio-inspired
optimization protruded chiral 8-(R)-drimane fused oxazinone D as a lead, considering …

Total synthesis of (+)-aureol

KKW Kuan, HP Pepper, WM Bloch, JH George - Organic letters, 2012 - ACS Publications
A total synthesis of the marine sponge meroterpenoid (+)-aureol has been achieved in 12
steps (6% overall yield) from (+)-sclareolide. Key steps of the synthesis include a …

Biomimetic Cationic Polyannulation Reaction Catalyzed by Bi(OTf)3: Cyclization of 1,6-Dienes, 1,6,10-Trienes, and Aryl Polyenes

J Godeau, S Olivero, S Antoniotti, E Dunach - Organic Letters, 2011 - ACS Publications
Nonactivated trienes and aryltrienes were cyclized into polycyclic compounds in good to
excellent yields under bismuth triflate catalysis in a biomimetic fashion. The reaction showed …

Divergent Synthesis of Bioactive Marine Meroterpenoids by Palladium‐Catalyzed Tandem Carbene Migratory Insertion

HS Wang, HJ Li, ZG Zhang… - European Journal of …, 2018 - Wiley Online Library
The divergent synthesis of (+)‐8‐epi‐puupehedione,(+)‐chromazonarol,(+)‐yahazunol, and
(+)‐yahazunone has been accomplished. The key steps were a palladium‐catalyzed …

Bio-inspired construction of a tetracyclic ring system with an avarane skeleton: total synthesis of dactyloquinone A

Y Wu, X Du, X Wang, H Liu, L Zhou, Y Tang… - Organic Chemistry …, 2022 - pubs.rsc.org
The asymmetric synthesis of the marine meroterpenoid dactyloquinone A was accomplished
for the first time. The key advanced intermediate, a 6/6/6/6 tetracyclic core derivative, was …