Transcriptional regulation of catabolic pathways is a central mechanism by which cells
respond to physiological cues to generate the energy required for anabolic pathways …

The innate cytokine system is involved in the response to excessive food intake. In this
review, we highlight recent advances in our understanding of the physiological role of three …

Cancer and metabolic disorders have emerged as major global health challenges, reaching
epidemic levels in recent decades. Often viewed as separate issues, metabolic disorders …

Insulin resistance (IR) during obesity is linked to adipose tissue macrophage (ATM)-driven
inflammation of adipose tissue. Whether anti-inflammatory glucocorticoids (GCs) at …

Intermittent fasting is a non-pharmacological dietary approach to management of obesity
and metabolic syndrome, involving periodic intervals of complete or near-complete …

Glucocorticoid receptor (GR) is a transcription factor that plays a crucial role in cancer
biology. In this study, we utilized an in silico‐designed GR activity signature to demonstrate …

The signals and structure of the tissues in which leukocytes reside critically mould leukocyte
function and development and have challenged our fundamental understanding of how to …

Fasting is part of many weight management and health-boosting regimens. Fasting causes
substantial metabolic adaptations in the liver that include the stimulation of fatty acid …

Nonalcoholic steatohepatitis (NASH) is epidemiologically associated with obesity and
diabetes and can lead to liver cirrhosis and hepatocellular carcinoma if left untreated. The …

Chronic liver diseases, primarily metabolic dysfunction-associated steatotic liver disease
(MASLD), harmful use of alcohol, or viral hepatitis, may result in liver fibrosis, cirrhosis, and …