Phytochemicals as potential anticancer drugs: time to ponder nature's bounty

MA Ashraf - BioMed research international, 2020 - Wiley Online Library
Medicinal plants have been used from the beginning of human civilization, which is mostly
evident from the ancient script and traditional herbal medicine recipe. Despite the historically …

Targeting the JAK/STAT signaling pathway using phytocompounds for cancer prevention and therapy

S Bose, S Banerjee, A Mondal, U Chakraborty… - Cells, 2020 - mdpi.com
Cancer is a prevalent cause of mortality around the world. Aberrated activation of Janus
kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway …

A comparative study on inclusion complex formation between formononetin and β-cyclodextrin derivatives through multiscale classical and umbrella sampling …

VK Bhardwaj, R Purohit - Carbohydrate Polymers, 2023 - Elsevier
Formononetin, a naturally occurring isoflavone exhibits a wide range of therapeutic
applications including antioxidant, anti-tumor, antiviral, anti-diabetic and neuroprotective …

Current herbal medicine as an alternative treatment in dentistry: In vitro, in vivo and clinical studies

ET Moghadam, M Yazdanian, E Tahmasebi… - European journal of …, 2020 - Elsevier
Since the time that human population comprehended the importance of general health
maintenance and the burden of disease, there has been a search for healing properties in …

The pleiotropic role of transcription factor STAT3 in oncogenesis and its targeting through natural products for cancer prevention and therapy

M Garg, MK Shanmugam, V Bhardwaj… - Medicinal research …, 2021 - Wiley Online Library
Signal transducer and activator of transcription 3 (STAT3) is one of the crucial transcription
factors, responsible for regulating cellular proliferation, cellular differentiation, migration …

Nanoparticle drug delivery systems for synergistic delivery of tumor therapy

D Chen, X Liu, X Lu, J Tian - Frontiers in Pharmacology, 2023 - frontiersin.org
Nanoparticle drug delivery systems have proved anti-tumor effects; however, they are not
widely used in tumor therapy due to insufficient ability to target specific sites, multidrug …

The anti-cancerous activity of adaptogenic herb Astragalus membranaceus

A Sheik, K Kim, GL Varaprasad, H Lee, S Kim, E Kim… - Phytomedicine, 2021 - Elsevier
Background Cancer is the most dreadful disease increasing rapidly causing an economic
burden globally. A standardized chemotherapy regimen planned with curative intent …

Targeting STAT3 signaling pathway in cancer by agents derived from Mother Nature

CD Mohan, S Rangappa, HD Preetham… - Seminars in cancer …, 2022 - Elsevier
Signal transducer and activator of transcription (STAT) proteins are latent transcription
factors that reside in the cytoplasm of several types of cells. In canonical signaling, upon …

Beneficial Effects of Astragalus membranaceus (Fisch.) Bunge Extract in Controlling Inflammatory Response and Preventing Asthma Features

D D'Avino, I Cerqua, H Ullah, M Spinelli… - International Journal of …, 2023 - mdpi.com
Astragalus membranaceus (Fisch.) Bunge root is used as herbal medicine for its
immunomodulating activities in Chinese medicine. Recently, beneficial properties of A …

Tetrandrine: a review of its anticancer potentials, clinical settings, pharmacokinetics and drug delivery systems

F Luan, X He, N Zeng - Journal of Pharmacy and Pharmacology, 2020 - academic.oup.com
Objectives Tetrandrine, a natural bisbenzylisoquinoline alkaloid, possesses promising
anticancer activities on diverse tumours. This review provides systematically organized …