REM sleep loss increases brain excitability: Role of noradrenalin and its mechanism of action

BN Mallick, A Singh - Sleep medicine reviews, 2011 - Elsevier
Ever since the discovery of rapid eye movement sleep (REMS), studies have been
undertaken to understand its necessity, function and mechanism of action on normal …

Role of norepinephrine in the regulation of rapid eye movement sleep

BN Mallick, S Majumdar, M Faisal, V Yadav… - Journal of …, 2002 - Springer
Sleep and wakefulness are instinctive behaviours that are present across the animal
species. Rapid eye movement (REM) sleep is a unique biological phenomenon expressed …

Increased apoptosis in rat brain after rapid eye movement sleep loss

S Biswas, P Mishra, BN Mallick - Neuroscience, 2006 - Elsevier
Rapid eye movement (REM) sleep loss impairs several physiological, behavioral and
cellular processes; however, the mechanism of action was unknown. To understand the …

Rapid eye movement sleep deprivation induces neuronal apoptosis by noradrenaline acting on Alpha1 adrenoceptor and by triggering mitochondrial intrinsic pathway

BI Somarajan, MA Khanday, BN Mallick - Frontiers in neurology, 2016 - frontiersin.org
Many neurodegenerative disorders are associated with rapid eye movement sleep (REMS)
loss; however, the mechanism was unknown. As REMS loss elevates noradrenaline (NA) …

Effect of paradoxical sleep deprivation on oxidative stress parameters in brain regions of adult and old rats

R Singh, J Kiloung, S Singh, D Sharma - Biogerontology, 2008 - Springer
The present study examined the effects of paradoxical sleep (PS) deprivation on the
oxidative stress parameters: lipid peroxidation, superoxide dismutase, glutathione …

Rapid eye movement sleep deprivation impairs neuronal plasticity and reduces hippocampal neuronal arborization in male albino rats: Noradrenaline is involved in …

S Giri, A Ranjan, A Kumar, M Amar… - Journal of …, 2021 - Wiley Online Library
Rapid eye movement sleep (REMS) favors brain development and memory, while it is
decreased in neurodegenerative diseases. REMS deprivation (REMSD) affects several …

Mild electrical stimulation of pontine tegmentum around locus coeruleus reduces rapid eye movement sleep in rats

S Singh, BN Mallick - Neuroscience research, 1996 - Elsevier
The norepinephrinergic neurons in the locus coeruleus (LC) cease firing during REM sleep
(REMS) and increase firing during REMS deprivation. Most of the earlier studies used lesion …

[图书][B] Sleep deprivation: basic science, physiology and behavior

CA Kushida - 2004 - books.google.com
Analyzing ground-breaking research, this reference highlights the impact of sleep
deprivation on the well-being of the individual and society-presenting current theories on the …

Involvement of the α1-adrenoceptor in sleep–waking and sleep loss-induced anxiety behavior in zebrafish

A Singh, N Subhashini, S Sharma, BN Mallick - Neuroscience, 2013 - Elsevier
Sleep is a universal phenomenon in vertebrates, and its loss affects various behaviors.
Independent studies have reported that sleep loss increases anxiety; however, the detailed …

Neural mechanism of rapid eye movement sleep generation with reference to REM-OFF neurons in locus coeruleus

D Pal, BN Mallick - Indian Journal of Medical Research, 2007 - journals.lww.com
The noradrenergic (NA-ergic) rapid eye movement (REM)-OFF neurons in locus coeruleus
(LC) and cholinergic REM-ON neurons in laterodorsal/pedunculopontine tegmentum show a …