Unlocking exosome-based theragnostic signatures: deciphering secrets of ovarian cancer metastasis

S Mukherjee, S Nag, N Mukerjee, S Maitra… - ACS …, 2023 - ACS Publications
Ovarian cancer (OC) is a common gynecological cancer worldwide. Unfortunately, the lack
of early detection methods translates into a substantial cohort of women grappling with the …

Insulin-like growth factor-1 signaling in the tumor microenvironment: Carcinogenesis, cancer drug resistance, and therapeutic potential

AH Nwabo Kamdje, PF Seke Etet… - Frontiers in …, 2022 - frontiersin.org
The tumor microenvironment fuels tumorigenesis and induces the development of
resistance to anticancer drugs. A growing number of reports support that the tumor …

Platinum-induced upregulation of ITGA6 promotes chemoresistance and spreading in ovarian cancer

A Gambelli, A Nespolo… - EMBO Molecular …, 2024 - embopress.org
Abstract Platinum (PT)-resistant Epithelial Ovarian Cancer (EOC) grows as a metastatic
disease, disseminating in the abdomen and pelvis. Very few options are available for PT …

Proteomic profiles of peritoneal fluid-derived small extracellular vesicles correlate with patient outcome in ovarian cancer

M Quiralte, A Barquín… - The Journal of …, 2024 - Am Soc Clin Investig
Cancer-derived small extracellular vesicles (sEVs) are capable of modifying the tumor
microenvironment and promoting tumor progression. Ovarian cancer (OvCa) is a lethal …

ANXA9 facilitates S100A4 and promotes breast cancer progression through modulating STAT3 pathway

X Zhou, J Zhao, T Yan, D Ye, Y Wang, B Zhou… - Cell Death & …, 2024 - nature.com
Breast cancer has the highest global incidence and mortality rates among all cancer types.
Abnormal expression of the Annexin family has been observed in different malignant tumors …

Mechanisms of cell adhesion molecules in endocrine-related cancers: a concise outlook

Y Ruan, L Chen, D Xie, T Luo, Y Xu, T Ye… - Frontiers in …, 2022 - frontiersin.org
Chemotherapy is a critical treatment for endocrine-related cancers; however,
chemoresistance and disease recurrence remain a challenge. The interplay between cancer …

[HTML][HTML] Calcium signals and potential therapy targets in ovarian cancer

F Deng, M Fu, C Zhao, J Lei, T Xu… - International …, 2023 - spandidos-publications.com
Ovarian cancer (OC) is a deadly disease. The poor prognosis and high lethality of OC are
attributed to its high degrees of aggressiveness, resistance to chemotherapy and recurrence …

Screening and identification of key biomarkers associated with endometriosis using bioinformatics and next-generation sequencing data analysis

B Vastrad, C Vastrad - Egyptian Journal of Medical Human Genetics, 2024 - Springer
Background Endometriosis is a common cause of endometrial-type mucosa outside the
uterine cavity with symptoms such as painful periods, chronic pelvic pain, pain with …

[图书][B] Cancer Associated Fibroblasts Provide a Cancer Stem Cell Niche that Leads to Disease Relapse in Ovarian Cancer

Y Fang - 2023 - search.proquest.com
Epithelial ovarian cancer is the most lethal gynecologic malignancy with a 5-year survival
rate of only 48%. While most ovarian cancer patients respond to chemotherapy initially …

Epithelial tumor compartment-and adjacent stromal compartment-specific expression of PARP1 in different anatomical sites in patients with HGSOC

C Berkel, E Cacan - Genome Instability & Disease, 2022 - Springer
High-grade serous ovarian carcinoma (HGSOC) is responsible for the majority of ovarian
cancer-associated deaths. PARP (poly-(ADP-ribose) polymerase) inhibitors …