Artificial intelligence and machine learning approaches to facilitate therapeutic drug management and model-informed precision dosing

EA Poweleit, AA Vinks, T Mizuno - Therapeutic drug monitoring, 2023 - journals.lww.com
Background: Therapeutic drug monitoring (TDM) and model-informed precision dosing
(MIPD) have greatly benefitted from computational and mathematical advances over the …

[HTML][HTML] AI for life: Trends in artificial intelligence for biotechnology

A Holzinger, K Keiblinger, P Holub, K Zatloukal… - New …, 2023 - Elsevier
Due to popular successes (eg, ChatGPT) Artificial Intelligence (AI) is on everyone's lips
today. When advances in biotechnology are combined with advances in AI unprecedented …

[HTML][HTML] Artificial intelligence in the field of pharmacy practice: A literature review

SH Chalasani, J Syed, M Ramesh, V Patil… - Exploratory Research in …, 2023 - Elsevier
Artificial intelligence (AI) is a transformative technology used in various industrial sectors
including healthcare. In pharmacy practice, AI has the potential to significantly improve …

Automated warfarin dose prediction for Asian, American, and Caucasian populations using a deep neural network

V Jahmunah, S Chen, SL Oh, UR Acharya… - Computers in biology …, 2023 - Elsevier
Existing warfarin dose prediction algorithms based on pharmacogenetics and clinical
parameters have not been used clinically due to the absence of external validation, lack of …

Advancing precision medicine: A review of innovative In Silico approaches for drug development, clinical pharmacology and personalized healthcare

L Marques, B Costa, M Pereira, A Silva, J Santos… - Pharmaceutics, 2024 - mdpi.com
The landscape of medical treatments is undergoing a transformative shift. Precision
medicine has ushered in a revolutionary era in healthcare by individualizing diagnostics and …

Artificial Intelligence in battling infectious diseases: A transformative role

C Li, G Ye, Y Jiang, Z Wang, H Yu… - Journal of Medical …, 2024 - Wiley Online Library
It is widely acknowledged that infectious diseases have wrought immense havoc on human
society, being regarded as adversaries from which humanity cannot elude. In recent years …

A machine learning approach to personalized dose adjustment of lamotrigine using noninvasive clinical parameters

X Zhu, W Huang, H Lu, Z Wang, X Ni, J Hu, S Deng… - Scientific Reports, 2021 - nature.com
The pharmacokinetic variability of lamotrigine (LTG) plays a significant role in its dosing
requirements. Our goal here was to use noninvasive clinical parameters to predict the dose …

Machine learning models to predict the warfarin discharge dosage using clinical information of inpatients from South Korea

H Choi, HJ Kang, I Ahn, H Gwon, Y Kim, H Seo… - Scientific reports, 2023 - nature.com
As warfarin has a narrow therapeutic window and obvious response variability among
individuals, it is difficult to rapidly determine personalized warfarin dosage. Adverse drug …

Development of a system to support warfarin dose decisions using deep neural networks

H Lee, HJ Kim, HW Chang, DJ Kim, J Mo, JE Kim - Scientific reports, 2021 - nature.com
The first aim of this study was to develop a prothrombin time international normalized ratio
(PT INR) prediction model. The second aim was to develop a warfarin maintenance dose …

[HTML][HTML] Machine learning in medication prescription: A systematic review

A Iancu, I Leb, HU Prokosch, W Rödle - International Journal of Medical …, 2023 - Elsevier
Background Medication prescription is a complex process that could benefit from current
research and development in machine learning through decision support systems …