Targeting cancer with phytochemicals via their fine tuning of the cell survival signaling pathways
The role of phytochemicals as potential prodrugs or therapeutic substances against tumors
has come in the spotlight in the very recent years, thanks to the huge mass of encouraging …
has come in the spotlight in the very recent years, thanks to the huge mass of encouraging …
Genome-protecting compounds as potential geroprotectors
Throughout life, organisms are exposed to various exogenous and endogenous factors that
cause DNA damages and somatic mutations provoking genomic instability. At a young age …
cause DNA damages and somatic mutations provoking genomic instability. At a young age …
[HTML][HTML] Long-term exposure to genistein inhibits the proliferation of gallbladder cancer by downregulating the MCM complex
Y Geng, S Chen, Y Yang, H Miao, X Li, G Li, J Ma… - Science Bulletin, 2022 - Elsevier
Soy isoflavones are natural tyrosine kinase inhibitors closely associated with decreased
morbidity and mortality of various tumors. The activation of tyrosine kinases such as ERBB2 …
morbidity and mortality of various tumors. The activation of tyrosine kinases such as ERBB2 …
Modulation of inflammation by phytochemicals to enhance efficacy and reduce toxicity of cancer chemotherapy
Abstract Treatment of cancer with chemotherapeutic drugs is associated with numerous
adverse effects as well as the eventual development of resistance to chemotherapy. There is …
adverse effects as well as the eventual development of resistance to chemotherapy. There is …
Epigenetic Modifiers as Game Changers for Healthy Aging
S Sharma, R Bhonde - Rejuvenation Research, 2023 - liebertpub.com
Epigenetic alterations during aging are manifested with altered gene expression linking it to
lifespan regulation, genetic instability, and diseases. Diet and epigenetic modifiers exert a …
lifespan regulation, genetic instability, and diseases. Diet and epigenetic modifiers exert a …
Characterization of flavonoids with potent and subtype-selective actions on estrogen receptors alpha and beta
The initial step in estrogen-regulated transcription is the binding of a ligand to its cognate
receptors, named estrogen receptors (ERα and ERβ). Phytochemicals present in foods and …
receptors, named estrogen receptors (ERα and ERβ). Phytochemicals present in foods and …
The effect of diet components on cancer with epigenetic mechanisms
B Özyalçin, N Sanlier - Trends in Food Science & Technology, 2020 - Elsevier
Cancer is the most important cause of mortality worldwide. Nutritional style, smoking
habGSits, body weight and some lifestyle factors such as modifiable risk factors are also …
habGSits, body weight and some lifestyle factors such as modifiable risk factors are also …
Carotid artery disease in post‐stroke survivors and effects of enriched environment on stroke pathology in a mouse model of carotid artery stenosis
Aims Carotid artery disease (CAD) is an important risk factor for stroke. We first evaluated
CAD and stroke pathology in elderly post‐stroke survivors. To simulate CAD, we assessed …
CAD and stroke pathology in elderly post‐stroke survivors. To simulate CAD, we assessed …
Genistein in focus: pharmacological effects and immune pathway modulation in cancer
P Goleij, MAK Tabari, M Khandan, M Poudineh… - Naunyn-Schmiedeberg's …, 2024 - Springer
Cancer is a significant global health concern, responsible for mortality and morbidity of
individuals. It is characterized by uncontrolled cellular growth, tumor formation, and potential …
individuals. It is characterized by uncontrolled cellular growth, tumor formation, and potential …
[PDF][PDF] Carotid Artery Disease in Post-Stroke Survivors and Effects of Enriched Environment on Stroke
Aims: Carotid artery disease (CAD) is an important risk factor for stroke. We first evaluated
CAD and stroke pathology in elderly post-stroke survivors. To simulate CAD, we assessed …
CAD and stroke pathology in elderly post-stroke survivors. To simulate CAD, we assessed …