Liquid–liquid phase separation (LLPS) is a novel principle for explaining the precise spatial
and temporal regulation in living cells. LLPS compartmentalizes proteins and nucleic acids …

The development and application of whole genome sequencing technology has greatly
broadened our horizons on the capabilities of long non-coding RNAs (lncRNAs). LncRNAs …

Background Long non-coding RNA (LncRNA) controls cell proliferation and plays a
significant role in the initiation and progression of esophageal squamous cell carcinoma …

Squamous cell carcinomas (SCCs) comprise one of the most common histologic types of
human cancer. Transcriptional dysregulation of SCC cells is orchestrated by tumor protein …

Background & Aims We investigated the transcriptome of esophageal squamous cell
carcinoma (ESCC) cells, activity of gene regulatory (enhancer and promoter regions), and …

Long non-coding RNAs (lncRNAs) have been proven to play important roles in
transcriptional processes and various biological functions. Establishing a comprehensive …

Increasing evidence has revealed the roles of long noncoding RNAs (lncRNAs) as tumor
biomarkers. Here, we introduce an immune-associated nine-lncRNA signature for predicting …

Idiopathic pulmonary fibrosis (IPF) is characterized by lung scarring and has no effective
treatment. Fibroblast-to-myofibroblast differentiation and myofibroblast proliferation and …

Epigenetic alterations, along with genetic alterations, have long been regarded as the most
important mechanism participating in carcinogenesis. DNA methylation, histone …

Background Lung adenocarcinoma (LUAD) is the leading cause of death worldwide.
However, the roles of long noncoding RNAs (lncRNAs) hijacked by super-enhancers (SEs) …