Axon–glia interactions in the ascending auditory system

DC Kohrman, BC Borges, LR Cassinotti… - Developmental …, 2021 - Wiley Online Library
The auditory system detects and encodes sound information with high precision to provide a
high‐fidelity representation of the environment and communication. In mammals, detection …

Molecular and clinical significance of fibroblast growth factor 2 in development and regeneration of the auditory system

M Jeong, K Bojkovic, V Sagi… - Frontiers in Molecular …, 2021 - frontiersin.org
The fibroblast growth factor 2 (FGF2) is a member of the FGF family which is involved in key
biological processes including development, cellular proliferation, wound healing, and …

A spatial and temporal gradient of Fgf differentially regulates distinct stages of neural development in the zebrafish inner ear

S Vemaraju, H Kantarci, MS Padanad, BB Riley - PLoS genetics, 2012 - journals.plos.org
Neuroblasts of the statoacoustic ganglion (SAG) initially form in the floor of the otic vesicle
during a relatively brief developmental window. They soon delaminate and undergo a …

Inactivation of fibroblast growth factor receptor signaling in myelinating glial cells results in significant loss of adult spiral ganglion neurons accompanied by age …

SJ Wang, M Furusho, C D'sa, S Kuwada… - Journal of …, 2009 - Wiley Online Library
Hearing loss has been attributed to many factors, including degeneration of sensory
neurons in the auditory pathway and demyelination along the cochlear nerve. Fibroblast …

Localization of prosaposin in rat cochlea

T Terashita, S Saito, K Miyawaki, M Hyodo… - Neuroscience …, 2007 - Elsevier
Prosaposin, the precursor of the sphingolipid hydrolase activator proteins called saposins A,
B, C, and D, is abundant in the nervous system and muscles. Besides its role as the …

Contuse lesion of the rat spinal cord of moderate intensity leads to a higher time-dependent secondary neurodegeneration than severe one: An open-window for …

MSR Andrade, FR Hanania, K Daci, RJA Leme… - Tissue and Cell, 2008 - Elsevier
Secondary neurodegeneration takes place in the surrounding tissue of spinal cord trauma
and modifies substantially the prognosis, considering the small diameter of its transversal …

mRNA abundance of neurogenic factors correlates with hearing capacity in auditory brainstem nuclei of the rat

J Engert, J Doll, B Vona, T Ehret Kasemo, B Spahn… - Life, 2023 - mdpi.com
Neural stem cells (NSCs) have previously been described up to the adult stage in the rat
cochlear nucleus (CN). A decreasing neurogenic potential was observed with critical …

Differential regulation of FGF-2 in neurons and reactive astrocytes of axotomized rat hypoglossal nucleus. A possible therapeutic target for neuroprotection in …

GP de Oliveira, T Duobles, P Castelucci, G Chadi - Acta histochemica, 2010 - Elsevier
Despite the favorable treatment of cranial nerve neuropathology in adulthood, some cases
are resistant to therapy leading to permanent functional impairments. In many cases …

Influence of topical application of basic fibroblast growth factor upon inner ear

KI KaseKei-Ichi, T Iwanaga… - … —Head and Neck …, 2008 - journals.sagepub.com
Background Basic fibroblast growth factor (b-FGF) has recently been shown to have a
positive effect on the treatment of postoperative mastoid cavity problem, but its ototoxicity …

Neuropeptide Y in rat spiral ganglion neurons and inner hair cells of organ of corti and effects of a nontraumatic acoustic stimulation

VC Gomide, MR Laureano, GA Silveira… - International Journal of …, 2009 - Taylor & Francis
Neuropeptide Y (NPY) is an important neuromodulator found in central and peripheral
neurons. NPY was investigated in the peripheral auditory pathway of conventional housed …