Pseudomonas aeruginosa Lifestyle: A Paradigm for Adaptation, Survival, and Persistence

MF Moradali, S Ghods, BHA Rehm - Frontiers in cellular and infection …, 2017 - frontiersin.org
Pseudomonas aeruginosa is an opportunistic pathogen affecting immunocompromised
patients. It is known as the leading cause of morbidity and mortality in cystic fibrosis (CF) …

Biofilms and cyclic di-GMP (c-di-GMP) signaling: lessons from Pseudomonas aeruginosa and other bacteria

M Valentini, A Filloux - Journal of Biological Chemistry, 2016 - ASBMB
The cyclic di-GMP (c-di-GMP) second messenger represents a signaling system that
regulates many bacterial behaviors and is of key importance for driving the lifestyle switch …

Cyclic di-GMP: the first 25 years of a universal bacterial second messenger

U Römling, MY Galperin… - … and Molecular Biology …, 2013 - Am Soc Microbiol
Twenty-five years have passed since the discovery of cyclic dimeric (3′→ 5′) GMP (cyclic
di-GMP or c-di-GMP). From the relative obscurity of an allosteric activator of a bacterial …

A surface-induced asymmetric program promotes tissue colonization by Pseudomonas aeruginosa

BJ Laventie, M Sangermani, F Estermann, P Manfredi… - Cell host & …, 2019 - cell.com
The opportunistic human pathogen Pseudomonas aeruginosa effectively colonizes host
epithelia using pili as primary adhesins. Here we uncover a surface-specific asymmetric …

Regulation of biofilm formation in Pseudomonas and Burkholderia species

M Fazli, H Almblad, ML Rybtke… - Environmental …, 2014 - Wiley Online Library
In the present review, we describe and compare the molecular mechanisms that are
involved in the regulation of biofilm formation by P seudomonas putida, P seudomonas …

Matrix exopolysaccharides; the sticky side of biofilm formation

E Maunders, M Welch - FEMS microbiology letters, 2017 - academic.oup.com
Abstract The Gram-negative pathogen Pseudomonas aeruginosa is found ubiquitously
within the environment and is recognised as an opportunistic human pathogen that …

Exoelectrogens in microbial fuel cells toward bioelectricity generation: a review

R Kumar, L Singh, ZA Wahid… - International Journal of …, 2015 - Wiley Online Library
Exoelectrogens are catalytic microorganisms competent to shuttle electrons exogenously to
the electrode surface without utilizing artificial mediators. Diverse microorganisms acting as …

Genetic control of bacterial biofilms

KI Wolska, AM Grudniak, Z Rudnicka… - Journal of applied …, 2016 - Springer
Nearly all bacterial species, including pathogens, have the ability to form biofilms. Biofilms
are defined as structured ecosystems in which microbes are attached to surfaces and …

Pseudomonas aeruginosa rugose small-colony variants evade host clearance, are hyper-inflammatory, and persist in multiple host environments

MJ Pestrak, SB Chaney, HC Eggleston… - PLoS …, 2018 - journals.plos.org
Pseudomonas aeruginosa causes devastating infections in immunocompromised
individuals. Once established, P. aeruginosa infections become incredibly difficult to treat …

[HTML][HTML] C-di-GMP synthesis: structural aspects of evolution, catalysis and regulation

T Schirmer - Journal of molecular biology, 2016 - Elsevier
Cellular levels of the second messenger cyclic di-guanosine monophosphate (c-di-GMP)
are determined by the antagonistic activities of diguanylate cyclases and specific …