Retinal ganglion cells—diversity of cell types and clinical relevance
Retinal ganglion cells (RGCs) are the bridging neurons that connect the retinal input to the
visual processing centres within the central nervous system. There is a remarkable diversity …
visual processing centres within the central nervous system. There is a remarkable diversity …
Light and cognition: roles for circadian rhythms, sleep, and arousal
Light exerts a wide range of effects on mammalian physiology and behavior. As well as
synchronizing circadian rhythms to the external environment, light has been shown to …
synchronizing circadian rhythms to the external environment, light has been shown to …
[HTML][HTML] Light and the laboratory mouse
Light exerts widespread effects on physiology and behaviour. As well as the widely-
appreciated role of light in vision, light also plays a critical role in many non-visual …
appreciated role of light in vision, light also plays a critical role in many non-visual …
The role of sleep deprivation and circadian rhythm disruption as risk factors of Alzheimer's disease
Emerging evidence suggests that sleep deprivation (SD) and circadian rhythm disruption
(CRD) may interact and increase the risk for the development of Alzheimer's disease (AD) …
(CRD) may interact and increase the risk for the development of Alzheimer's disease (AD) …
[HTML][HTML] Optogenetics for visual restoration: from proof of principle to translational challenges
Degenerative retinal disorders are a diverse family of diseases commonly leading to
irreversible photoreceptor death, while leaving the inner retina relatively intact. Over recent …
irreversible photoreceptor death, while leaving the inner retina relatively intact. Over recent …
The circadian clock and metabolic homeostasis: entangled networks
LVM de Assis, H Oster - Cellular and Molecular Life Sciences, 2021 - Springer
The circadian clock exerts an important role in systemic homeostasis as it acts a keeper of
time for the organism. The synchrony between the daily challenges imposed by the …
time for the organism. The synchrony between the daily challenges imposed by the …
Optogenetic approaches to vision restoration
Inherited retinal disease (IRD) affects about 1 in 3000 to 1 in 5000 individuals and is now
believed to be the most common cause of blindness registration in developed countries …
believed to be the most common cause of blindness registration in developed countries …
Dim light in the evening causes coordinated realignment of circadian rhythms, sleep, and short-term memory
Light provides the primary signal for entraining circadian rhythms to the day/night cycle. In
addition to rods and cones, the retina contains a small population of photosensitive retinal …
addition to rods and cones, the retina contains a small population of photosensitive retinal …
Melanopsin‐expressing ganglion cells in human retina: Morphology, distribution, and synaptic connections
Melanopsin‐expressing retinal ganglion cells are intrinsically photosensitive cells that are
involved in non‐image forming visual processes such as the pupillary light reflex and …
involved in non‐image forming visual processes such as the pupillary light reflex and …
Myopes have significantly higher serum melatonin concentrations than non‐myopes
S Kearney, L O'Donoghue… - Ophthalmic and …, 2017 - Wiley Online Library
Purpose Experimental animal models of myopia demonstrate that higher melatonin (Mel)
and lower dopamine (DA) concentrations actively promote axial elongation. This study …
and lower dopamine (DA) concentrations actively promote axial elongation. This study …