The diagnostic and therapeutic potential of galectin-3 in cardiovascular diseases

G Sygitowicz, A Maciejak-Jastrzębska, D Sitkiewicz - Biomolecules, 2021 - mdpi.com
Galectin-3 plays a prominent role in chronic inflammation and has been implicated in the
development of many disease conditions, including heart disease. Galectin-3, a regulatory …

Clinical application of serum microRNAs in atherosclerotic coronary artery disease

A Kabłak-Ziembicka, R Badacz… - Journal of Clinical …, 2022 - mdpi.com
MicroRNAs (miRs) are promising diagnostic, prognostic and therapeutic biomolecules for
atherosclerotic cardiovascular disease. Atherosclerotic occlusive disease concerns a large …

Novel biomarkers and their role in the diagnosis and prognosis of acute coronary syndrome

M Katsioupa, I Kourampi, E Oikonomou, V Tsigkou… - Life, 2023 - mdpi.com
The burden of cardiovascular diseases and the critical role of acute coronary syndrome
(ACS) in their progression underscore the need for effective diagnostic and prognostic tools …

The roles of microRNAs in the cardiovascular system

F Nappi, SS Avtaar Singh, V Jitendra, A Alzamil… - International Journal of …, 2023 - mdpi.com
The discovery of miRNAs and their role in disease represent a significant breakthrough that
has stimulated and propelled research on miRNAs as targets for diagnosis and therapy …

Unlocking the potential of microRNAs: machine learning identifies key biomarkers for myocardial infarction diagnosis

M Samadishadlou, R Rahbarghazi, Z Piryaei… - Cardiovascular …, 2023 - Springer
Background MicroRNAs (miRNAs) play a crucial role in regulating adaptive and
maladaptive responses in cardiovascular diseases, making them attractive targets for …

Towards real-time myocardial infarction diagnosis: a convergence of machine learning and ion-exchange membrane technologies leveraging miRNA signatures

X Ren, R Zhou, G Ronan, SG Ozcebe, J Ji, S Senapati… - Lab on a Chip, 2024 - pubs.rsc.org
Rapid diagnosis of acute myocardial infarction (AMI) is crucial for optimal patient
management. Accurate diagnosis and time of onset of an acute event can influence …

An exploration into the diagnostic capabilities of microRNAs for myocardial infarction using machine learning

M Samadishadlou, R Rahbarghazi, K Kavousi, F Bani - Biology Direct, 2024 - Springer
MicroRNAs (miRNAs) have shown potential as diagnostic biomarkers for myocardial
infarction (MI) due to their early dysregulation and stability in circulation after MI. Moreover …

[HTML][HTML] Multiple Genetic Polymorphisms within microRNA Targets and Homologous microRNA-Binding Sites: Two More Factors Influencing microRNA-Mediated …

M Giurgiu, R Kaltenbach, F Ahrend, S Weeks, H Clifton… - 2023 - intechopen.com
Abstract miRNA-mRNA interaction depends on multiple factors such as 3'UTR isoforms, the
cell and tissue-specific expression levels of RNA-binding proteins, the sequence context …

miR-22-3p as a potential biomarker for coronary artery disease based on integrated bioinformatics analysis

M Zhang, Y Hu, H Li, X Guo, J Zhong, S He - Frontiers in Genetics, 2022 - frontiersin.org
Background: Coronary artery disease (CAD) is a common cardiovascular disease that has
attracted attention worldwide due to its high morbidity and mortality. Recent studies have …

Cardiovascular Biomarkers in Acute Myocardial Infarction

C Vassalle, L Sabatino, A Pepe - Ischemic Heart Disease: From Diagnosis …, 2023 - Springer
The use of a large number of cardiovascular biomarkers, meant to complement the use of
the electrocardiogram, echocardiography cardiac imaging, and clinical symptom …