Macromolecular crowding effects on protein dynamics
Macromolecular crowding experiments bridge the gap between in-vivo and in-vitro studies
by mimicking some of the cellular complexities like high viscosity and limited space, while …
by mimicking some of the cellular complexities like high viscosity and limited space, while …
Understanding the intricacy of protein in hydrated deep eutectic solvent: Solvation dynamics, conformational fluctuation dynamics, and stability
Deep eutectic solvents (DESs) are potential biocatalytic media due to their easy preparation,
fine-tuneability, biocompatibility, and most importantly, due to their ability to keep protein …
fine-tuneability, biocompatibility, and most importantly, due to their ability to keep protein …
Does Viscosity Decoupling Guarantee Dynamic Heterogeneity? A Clue through an Excitation and Emission Wavelength-Dependent Time-Resolved Fluorescence …
Traditionally, deviation from Stokes–Einstein–Debye (SED) relation in terms of viscosity
dependence of medium dynamics, ie, τ x∝(η T) p with p≠ 1, is taken as a signature of …
dependence of medium dynamics, ie, τ x∝(η T) p with p≠ 1, is taken as a signature of …
Associated water dynamics might be a key factor affecting protein stability in the crowded milieu
Over the past 20 years, the most studied and debated aspect of macromolecular crowding is
how it affects protein stability. Traditionally, it is explained by a delicate balance between the …
how it affects protein stability. Traditionally, it is explained by a delicate balance between the …
Multiple evidences for molecular level heterogeneity in a non-ionic biocatalytic deep eutectic solvent
Deep eutectic solvents (DESs) are new-generation solvents with exquisite and tuneable
properties. Molecular-level heterogeneity has been identified as an intriguing feature of such …
properties. Molecular-level heterogeneity has been identified as an intriguing feature of such …
Synergistic Chloroform–Methanol Binary Solvent Mixture Is Inherently Spatially and Dynamically Heterogeneous
Nonideality in a binary solvent mixture is manifested through anomalies in various physical
properties like viscosity, dielectric constant, polarity, freezing point, boiling point, and so …
properties like viscosity, dielectric constant, polarity, freezing point, boiling point, and so …
The effect of chrysin binding on the conformational dynamics and unfolding pathway of human serum albumin
I Bisaria, C Chauhan, SA Muthu, S Parvez… - Spectrochimica Acta Part …, 2024 - Elsevier
Studies on the interactions between ligands and proteins provide insights into how a
possible medication alters the structures and activities of the target or carrier proteins. The …
possible medication alters the structures and activities of the target or carrier proteins. The …
The shift of excitation spectra at blue edge of emission (BEEmS) as a new methodology to probe heterogeneity
Many current methods for detecting molecular-level heterogeneity are complex and require
stringent data analysis, limiting their widespread use. Herein, we propose a novel edge …
stringent data analysis, limiting their widespread use. Herein, we propose a novel edge …