A survey of the year 2007 literature on applications of isothermal titration calorimetry

S Bjelić, I Jelesarov - Journal of Molecular Recognition, 2008 - Wiley Online Library
Elucidation of the energetic principles of binding affinity and specificity is a central task in
many branches of current sciences: biology, medicine, pharmacology, chemistry, material …

Immobilization of laccase-ABTS system for the development of a continuous flow packed bed bioreactor for decolorization of textile effluent

S Sondhi, R Kaur, S Kaur, PS Kaur - International journal of biological …, 2018 - Elsevier
Decolourization of textile effluent is always being a problem of major concern for the safe
disposal of effluent water in river stream. Due to intense colour of the effluent water, even …

Efficient pretreatment of lignocellulosic biomass with high recovery of solid lignin and fermentable sugars using Fenton reaction in a mixed solvent

HT Yu, BY Chen, BY Li, MC Tseng, CC Han… - Biotechnology for …, 2018 - Springer
Background Pretreatment of biomass to maximize the recovery of fermentable sugars as
well as to minimize the amount of enzyme inhibitors formed during the pretreatment is a …

DMSO: a mixed-competitive inhibitor of human acetylcholinesterase

A Kumar, T Darreh-Shori - ACS chemical neuroscience, 2017 - ACS Publications
Dimethyl sulfoxide (DMSO) is the most common organic solvent used in biochemical and
cellular assays during drug discovery programs. Despite its wide use, the effect of DMSO on …

Dimethyl sulfoxide induced structural transformations and non-monotonic concentration dependence of conformational fluctuation around active site of lysozyme

S Roy, B Jana, B Bagchi - The Journal of Chemical Physics, 2012 - pubs.aip.org
Experimental studies have observed significant changes in both structure and function of
lysozyme (and other proteins) on addition of a small amount of dimethyl sulfoxide (DMSO) in …

Toward the development of dual‐targeted glyceraldehyde‐3‐phosphate dehydrogenase/trypanothione reductase inhibitors against Trypanosoma brucei and …

F Belluti, E Uliassi, G Veronesi, C Bergamini… - …, 2014 - Wiley Online Library
A significant improvement in the treatment of trypanosomiases has been achieved with the
recent development of nifurtimox–eflornithine combination therapy (NECT). As an alternative …

2-Phenoxy-1, 4-naphthoquinones: From a multitarget antitrypanosomal to a potential antitumor profile

F Prati, C Bergamini, MT Molina, F Falchi… - Journal of medicinal …, 2015 - ACS Publications
A small library of 2-phenoxy-1, 4-naphthoquinone and 2-phenoxy-1, 4-anthraquinone
derivatives was initially developed to optimize the antitrypanosomatid profile of the …

The use of dimethylsulfoxide as a solvent in enzyme inhibition studies: the case of aldose reductase

L Misuri, M Cappiello, F Balestri… - Journal of enzyme …, 2017 - Taylor & Francis
Aldose reductase (AR) is an enzyme devoted to cell detoxification and at the same time is
strongly involved in the aetiology of secondary diabetic complications and the amplification …

Organic co‐solvents affect activity, stability and enantioselectivity of haloalkane dehalogenases

V Stepankova, J Damborsky… - Biotechnology …, 2013 - Wiley Online Library
Haloalkane dehalogenases are microbial enzymes with a wide range of biotechnological
applications, including biocatalysis. The use of organic co‐solvents to solubilize their …

Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase …

E Uliassi, G Fiorani, RL Krauth-Siegel… - European Journal of …, 2017 - Elsevier
Crassiflorone is a natural product with anti-mycobacterial and anti-gonorrhoeal properties,
isolated from the stem bark of the African ebony tree Diospyros crassiflora. We noticed that …