[HTML][HTML] Unveiling the significance of AKAP79/150 in the nervous system disorders: An emerging opportunity for future therapies?

CC Chu, YH Hu, GZ Li, J Chen, NN Zhang, YX Gu… - Neurobiology of …, 2025 - Elsevier
Abstract A-kinase anchoring protein 79/150 (AKAP79/150) is a crucial scaffolding protein
that positions various proteins at specific synaptic sites to modulate excitatory synaptic …

Plasticity mechanisms of genetically distinct Purkinje cells

S Voerman, R Broersen, SMA Swagemakers… - …, 2024 - Wiley Online Library
Despite its uniform appearance, the cerebellar cortex is highly heterogeneous in terms of
structure, genetics and physiology. Purkinje cells (PCs), the principal and sole output …

PP2B-dependent cerebellar plasticity sets the amplitude of the vestibulo-ocular reflex during juvenile development

B Wu, L Post, Z Lin, M Schonewille - Journal of Neuroscience, 2024 - Soc Neuroscience
Throughout life, the cerebellum plays a central role in the coordination and optimization of
movements, using cellular plasticity to adapt a range of behaviors. Whether these plasticity …

Phosphatase-independent activity of smooth-muscle calcineurin orchestrates a gene expression program leading to hypertension

PS Yunes-Leites, Y Sun, S Martinez-Martinez… - bioRxiv, 2023 - biorxiv.org
Objective: Angiotensin-II (Ang-II) drives pathological vascular wall remodeling in
hypertension and abdominal aortic aneurysm (AAA). Previous studies showed that the …

PP2B-dependent cerebellar plasticity sets the amplitude of an innate reflex during juvenile development

B Wu, L Post, Z Lin, M Schonewille - bioRxiv, 2024 - biorxiv.org
Throughout life, the cerebellum plays a central role in the coordination and optimization of
movements, using cellular plasticity to adapt a range of behaviors. If these plasticity …

[PDF][PDF] Targeting AKAP79/150 in Human Disorders: An Emerging Opportunity for Future Therapies?

CC Chu, CY Wu, L Zhou, J Xu, XP Lu… - Progress in …, 2023 - pneurobio.com
ABSTRACT A-kinase anchoring protein 79/150 (AKAP79/150) is an important scaffolding
protein, which anchors various important proteins to locate in appropriate synaptic domains …