Clinical development of metal complexes as photosensitizers for photodynamic therapy of cancer

J Karges - Angewandte chemie international edition, 2022 - Wiley Online Library
Cancer has emerged over the last decades as one of the deadliest diseases in the world.
Among the most commonly used techniques (ie surgery, immunotherapy, radiotherapy or …

Ru (II) containing photosensitizers for photodynamic therapy: A critique on reporting and an attempt to compare efficacy

MA Munegowda, A Manalac, M Weersink… - Coordination chemistry …, 2022 - Elsevier
Ruthenium (II)-based coordination complexes have emerged as photosensitizers (PSs) for
photodynamic therapy (PDT) in oncology as well as antimicrobial indications and have great …

Theranostic imaging and multimodal photodynamic therapy and immunotherapy using the mTOR signaling pathway

H Zhou, D Tang, Y Yu, L Zhang, B Wang… - Nature …, 2023 - nature.com
Tumor metastases are considered the leading cause of cancer-associated deaths. While
clinically applied drugs have demonstrated to efficiently remove the primary tumor …

A supramolecular photosensitizer derived from an Arene-Ru (II) complex self-assembly for NIR activated photodynamic and photothermal therapy

G Xu, C Li, C Chi, L Wu, Y Sun, J Zhao, XH Xia… - Nature …, 2022 - nature.com
Effective photosensitizers are of particular importance for the widespread clinical utilization
of phototherapy. However, conventional photosensitizers are usually plagued by short …

NIR‐II Light Accelerated Prodrug Reduction of Pt (IV)‐Incorporating Pseudo Semiconducting Polymers for Robust Degradation and Maximized Photothermal/Chemo …

D Tang, H Zhou, M Cui, G Liang, H Zhang… - Advanced …, 2023 - Wiley Online Library
Selective activation of Pt (IV) prodrugs within tumors is particularly attractive because of their
low damage to normal tissues. However, current common activation via chemical …

Encapsulation of Ru (II) polypyridine complexes for tumor-targeted anticancer therapy

J Karges - BME frontiers, 2023 - spj.science.org
Ru (II) polypyridine complexes have attracted much attention as anticancer agents because
of their unique photophysical, photochemical, and biological properties. Despite their …

Recent progress in metal complexes functionalized nanomaterials for photodynamic therapy

F Wei, Z Chen, XC Shen, L Ji, H Chao - Chemical Communications, 2023 - pubs.rsc.org
Metal complexes have shown promise as photosensitizers for cancer diagnosis and
therapeutics. However, the vast majority of metal photosensitizers are not ideal and …

Classical polymers as highly tunable and designable heterogeneous photocatalysts

CTJ Ferguson, KAI Zhang - ACS Catalysis, 2021 - ACS Publications
Photocatalysis has emerged as a powerful synthetic tool to facilitate redox reactions with the
target of creating stable and tunable photocatalytic materials. A class of recyclable …

Incorporation of Ru (II) polypyridyl complexes into nanomaterials for cancer therapy and diagnosis

N Soliman, G Gasser, CM Thomas - Advanced Materials, 2020 - Wiley Online Library
Ru (II) polypyridyl complexes are compounds of great interest in cancer therapy due to their
unique photophysical, photochemical, and biological properties. For effective treatment, they …

Recent emergence of rhenium (I) tricarbonyl complexes as photosensitisers for cancer therapy

HS Liew, CW Mai, M Zulkefeli, T Madheswaran… - Molecules, 2020 - mdpi.com
Photodynamic therapy (PDT) is emerging as a significant complementary or alternative
approach for cancer treatment. PDT drugs act as photosensitisers, which upon using …