[HTML][HTML] Proceedings of chemistry, pharmacology, pharmacokinetics and synthesis of biflavonoids

X He, F Yang, X Huang - Molecules, 2021 - mdpi.com
Biflavonoids, composed of two monoflavonoid residues, occur naturally in angiosperms,
bryophytes, ferns, and gymnosperms. More than 592 biflavonoids have been structurally …

[HTML][HTML] Neurotherapeutic potential of kolaviron on neurotransmitter dysregulation, excitotoxicity, mitochondrial electron transport chain dysfunction and redox …

OB Ojo, ZA Amoo, IO Saliu, MT Olaleye… - Biomedicine & …, 2019 - Elsevier
This study investigated the effects of post-treatment with kolaviron on a 2-Vessel Occlusion
(2-VO) model of cerebral ischemia/reperfusion (I/R) injury in rats to ascertain its level of …

[HTML][HTML] MAPK/ERK 信号通路参与褪黑素对阿尔茨海默病大鼠小脑的神经保护作用

刘亭, 毕竟, 王盼, 任丽莉, 张露允, 隋汝波 - 2019 - html.rhhz.net
目的观察褪黑素能否通过MAPK/ERK 信号通路, 发挥对阿尔茨海默病大鼠小脑的神经保护作用.
方法将32 只♂ SD 大鼠随机分为4 组: 对照组, Aβ 1-42 侧脑室注射组(AD) …

CRMP2-derived peptide ST2-104 (R9-CBD3) protects SH-SY5Y neuroblastoma cells against Aβ25-35-induced neurotoxicity by inhibiting the pCRMP2/NMDAR2B …

Y Ji, Y Hu, J Ren, R Khanna, Y Yao, Y Chen… - Chemico-Biological …, 2019 - Elsevier
Collapsin response mediator protein 2 (CRMP2), by regulating voltage-gated calcium
channel activity, is a crucial regulator of neuronal excitability. Hyperphosphorylation of …

[HTML][HTML] Inhibitory potentials of Cymbopogon citratus oil against aluminium-induced behavioral deficits and neuropathology in rats

GI Temitayo, B Olawande… - Anatomy & Cell …, 2020 - synapse.koreamed.org
Cymbopogon citratus is a tropical phytomedicinal plant that is widely known for its
hypoglycemic, hypolipidemic, anxiolytic, sedative, antioxidative and anti-inflammatory …

Zingiber officinale Ethanolic Extract Attenuated Reserpine-Induced Depression-Like Condition and Associated Hippocampal Aberrations in Experimental Wistar Rats

JA Olanrewaju, JO Owolabi, IP Awodein… - Journal of …, 2020 - Taylor & Francis
Background Repeated and regimented treatment with reserpine causes depression-like
condition characterized by persistent mood disorder, feelings of severe despondency and …

[HTML][HTML] A Case for the Neuroprotective Potential of African Phytochemicals in the Management of Alzheimer's Disease

B Ben-Azu, AM Oghorodi, B Oritsemuelebi… - 2024 - intechopen.com
Alzheimer's disease (AD) is a chronic neurodegenerative disorder characterized of cognitive
dysfunction. AD is believed to be a global menace with an estimated fourfold increase in …

[HTML][HTML] Calcium Supplementation Ameliorates Cerebellar Oxidative Stress in Lactational Aluminum-induced Neurotoxicity in Rats

GO Omotoso, RA Olanrewaju, NO Amedu… - Basic and Clinical …, 2022 - ncbi.nlm.nih.gov
Methods: Four groups of juvenile rats were exposed via lactation to distilled water (control
group), aluminum (40 mg/kg/d), calcium supplement (50 mg/kg/d), and a combination of both …

[HTML][HTML] The protective effect of kolaviron on molecular, cellular, and behavioral characterization of cerebellum in the rat model of demyelinating diseases

GO Omotoso, LO Arietarhire, II Ukwubile… - Basic and Clinical …, 2020 - ncbi.nlm.nih.gov
Methods: Twenty-eight male Wistar rats were used in the present study. They were randomly
divided into 4 groups of 7 rats. Group A (control) received corn oil (0.5 mL/kg/d); group B …

[PDF][PDF] Neuroprotective Roles of Oleic Acid: An Antioxidant Status and Cerebellar Characterization in Rat Models of Aluminium Chloride-Induced Alzheimer Disease

KK Obasi - Ann Clin Med Case Rep, 2023 - acmcasereport.org
Neuroprotective Roles of Oleic Acid: An Antioxidant Status and Cerebellar Characterization in
Rat Models of Aluminium Chloride-I Page 1 Annals of Clinical and Medical Case Reports …