In this brief review and perspective, we address the question of whether the immune responses that bring about immune control of acute HIV infection are the same as, or distinct …
RL Rutishauser, L Trautmann - Current Opinion in HIV and AIDS, 2022 - journals.lww.com
We propose implications as to how this knowledge from natural infection can be applied in the design and evaluation of CD8+ T-cell-based remission strategies and offer questions to …
HIV-exposed seronegative individuals (HESIs) are a small fraction of persons who are multiply exposed to human immunodeficiency virus (HIV), but do not exhibit serological or …
MG Berg, A Olivo, BJ Harris, MA Rodgers, L James… - …, 2021 - thelancet.com
Background In-depth analysis of the HIV pandemic at its epicenter in the Congo basin has been hampered by 40 years of political unrest and lack of functional public health …
L Di Girolamo, M Ferrara, G Trevisan, BM Longo… - Virology Journal, 2023 - Springer
Background Elite controllers are able to control viral replication without antiretroviral therapy. Exceptional elite controllers do not show disease progression for more than 25 years …
FH Omondi, H Sudderuddin, A Shahid, NN Kinloch… - MBio, 2021 - Am Soc Microbiol
Curing HIV will require eliminating the reservoir of integrated, replication-competent proviruses that persist despite antiretroviral therapy (ART). Understanding the burden …
LW Lunardi, MAS Bragatte, GF Vieira - Brazilian Journal of Infectious …, 2021 - SciELO Brasil
The interaction of HIV-1, human leukocyte antigen (HLA), and elite controllers (EC) compose a still intricate triad. Elite controllers maintain a very low viral load and a normal CD4 count …
Quantile regression offers an invaluable tool to discern effects that would be missed by other conventional regression models, which are solely based on modeling conditional mean …
S Boppana, P Goepfert - F1000Research, 2018 - ncbi.nlm.nih.gov
HIV-infected individuals who maintain control of virus without antiretroviral therapy (ART) are called HIV controllers. The immune responses of these individuals suppress HIV viral …