From evolution to function: Two sides of the same CENP-B coin?
R Gamba, D Fachinetti - Experimental Cell Research, 2020 - Elsevier
The centromere is the nucleoproteic chromosomal structure necessary for accurate
chromosome segregation during cell division. One of the earliest centromeric proteins to be …
chromosome segregation during cell division. One of the earliest centromeric proteins to be …
DNA sequences in centromere formation and function
M Dumont, D Fachinetti - Centromeres and Kinetochores: Discovering the …, 2017 - Springer
Faithful chromosome segregation during cell division depends on the centromere, a
complex DNA/protein structure that links chromosomes to spindle microtubules. This …
complex DNA/protein structure that links chromosomes to spindle microtubules. This …
Epidermal growth factor receptor activation promotes ADA3 acetylation through the AKT-p300 pathway
ABSTRACT The ADA3 (Alteration/Deficiency in Activation 3) protein is an essential adaptor
component of several L ysine A cetyl t ransferase (KAT) complexes involved in chromatin …
component of several L ysine A cetyl t ransferase (KAT) complexes involved in chromatin …
Cell cycle roles for GCN5 revealed through genetic suppression
EL Petty, L Pillus - Biochimica et Biophysica Acta (BBA)-Gene Regulatory …, 2021 - Elsevier
The conserved acetyltransferase Gcn5 is a member of several complexes in eukaryotic cells,
playing roles in regulating chromatin organization, gene expression, metabolism, and cell …
playing roles in regulating chromatin organization, gene expression, metabolism, and cell …
[HTML][HTML] CENPB promotes the proliferation of hepatocellular carcinoma and is directly regulated by miR-29a
X Wang, L Luo, Y Zhang, G Liu, Z Fang, Z Xu… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is a significant global health concern as it ranks as the
sixth most common malignant tumor and the third leading cause of cancer-related deaths. In …
sixth most common malignant tumor and the third leading cause of cancer-related deaths. In …
Acetylation of mammalian ADA3 is required for its functional roles in histone acetylation and cell proliferation
Alteration/deficiency in activation 3 (ADA3) is an essential component of specific histone
acetyltransferase (HAT) complexes. We have previously shown that ADA3 is required for …
acetyltransferase (HAT) complexes. We have previously shown that ADA3 is required for …
ADA3 regulates normal and tumor mammary epithelial cell proliferation through c-MYC
Background We have established the critical role of ADA3 as a coactivator of estrogen
receptor (ER), as well as its role in cell cycle progression. Furthermore, we showed that …
receptor (ER), as well as its role in cell cycle progression. Furthermore, we showed that …
Mammalian ECD protein is a novel negative regulator of the PERK arm of the unfolded protein response
Mammalian Ecdysoneless (ECD) is a highly conserved ortholog of the DrosophilaEcd gene
product whose mutations impair the synthesis of Ecdysone and produce cell-autonomous …
product whose mutations impair the synthesis of Ecdysone and produce cell-autonomous …
抗着丝点抗体阳性患者体外受精结局分析
田雨晴， 周易尔， 范宇航， 陈素峰… - Journal of Zhejiang …, 2024 - pmc.ncbi.nlm.nih.gov
目的通过观察抗着丝点抗体(ACA) 阳性患者体外受精-胚胎移植和自然试孕结局,
探讨此类患者的生育策略. 方法采用病例对照研究回顾性分析2016 年6 月至2023 年6 …
探讨此类患者的生育策略. 方法采用病例对照研究回顾性分析2016 年6 月至2023 年6 …
CENP-A/CENP-B uncoupling in the evolutionary reshuffling of centromeres
E Cappelletti, FM Piras, M Biundo, E Raimondi… - bioRxiv, 2024 - biorxiv.org
Background While CENP-A is the epigenetic determinant of the centromeric function, the
role of CENP-B, the sole centromeric protein binding a specific DNA sequence (CENP-B …
role of CENP-B, the sole centromeric protein binding a specific DNA sequence (CENP-B …