Administration-time differences in effects of hypertension medications on ambulatory blood pressure regulation

RC Hermida, DE Ayala, JR Fernandez… - Chronobiology …, 2013 - Taylor & Francis
Specific features of the 24-h blood pressure (BP) pattern are linked to progressive injury of
target tissues and risk of cardiovascular disease (CVD) events. Several studies have …

Chronotherapy with low-dose aspirin for prevention of complications in pregnancy

DE Ayala, R Ucieda, RC Hermida - Chronobiology international, 2013 - Taylor & Francis
Preeclampsia and gestational hypertension are major contributors to perinatal morbidity and
mortality. Several studies aimed to test the effects of low-dose aspirin (ASA) in the …

Aspirin in the prevention of preeclampsia: the conundrum of how, who and when

R Shanmugalingam, A Hennessy… - Journal of human …, 2019 - nature.com
Aspirin is widely used in preventing early onset preeclampsia in women who are identified
as being high risk. Although the benefit of aspirin is increasingly evident and acknowledged …

Ascorbic acid (vitamin C) and iloprost attenuate the lung injury caused by ischemia/reperfusion of the lower extremities of rats

A Baltalarli, V Ozcan, B Ferda, H Aybek, M Sacar… - Annals of vascular …, 2006 - Elsevier
The objectives of this study were to compare the protective effects of ascorbic acid and
iloprost on lung injury caused by ischemia reperfusion (I/R) of the lower extremities of rats …

Ambulatory blood pressure control with bedtime aspirin administration in subjects with prehypertension

RC Hermida, DE Ayala, A Mojón… - American journal of …, 2009 - academic.oup.com
Background Aspirin has been found to prevent angiotensin II–induced hypertension and to
induce nitric oxide (NO) release from vascular endothelium. Low-dose aspirin has also been …

Cardiotoxicity of digitalis glycosides: roles of autonomic pathways, autacoids and ion channels

AT Demiryürek, S Demiryürek - Autonomic and autacoid …, 2005 - Wiley Online Library
Summary 1 Cardiac glycosides have been used for centuries as therapeutic agents for the
treatment of heart diaseases. In patients with heart failure, digoxin and the other glycosides …

Sex differences in the administration-time-dependent effects of low-dose aspirin on ambulatory blood pressure in hypertensive subjects

DE Ayala, RC Hermida - Chronobiology international, 2010 - Taylor & Francis
Previous studies have revealed sex differences in blood pressure (BP) regulation,
pathophysiology of hypertension, and treatment responses to medication. On the other …

The Role of Nitric Oxide in Digoxin‐Induced Arrhythmias in Guinea‐Pigs

S Altuǧ, Ö Uzun, AT Demiryürek, İ Çakıcı… - Pharmacology & …, 1999 - Wiley Online Library
We have investigated the effects of nitric oxide synthase inhibitor (L‐NAME), nitric oxide
precursor (L‐arginine) and nitric oxide donor (sodium nitroprusside) on digoxin‐induced …

Possible contribution of leukotrienes in the arrhythmogenic effects of digoxin on isolated guinea-pig hearts

Ş Gök, S Ülker, A Evinç - Pharmacology, 1998 - karger.com
The effect of a leukotriene D4 (LTD4) receptor antagonist, L-648,051, was investigated in
digoxin-induced cardiac toxicity in isolated guinea-pig hearts (Langendorff preparation) …

Effects of Platelet‐Activating Factor Antagonists WEB 2086 and BN 50730 on Digoxin‐Induced Arrhythmias *

İ Çakici, N Mataraci, S Ersoy, B Tunçtan… - Pharmacology & …, 1995 - Wiley Online Library
Effects of platelet‐activating receptor antagonists WEB 2086 (1.0‐30.0 mg· kg–1
intravenously) and BN 50730 (10.0 mg· kg–1 intravenously) alone or in combination with …