Plasma levels of the inflammatory biomarker high-sensitivity C-reactive protein (hsCRP)
predict vascular risk with an effect estimate as large as that of total or high-density …

Atherosclerosis, formerly considered a bland lipid storage disease, actually involves an
ongoing inflammatory response. Recent advances in basic science have established a …

Advancing our understanding of mechanisms of immune regulation in allergy, asthma,
autoimmune diseases, tumor development, organ transplantation, and chronic infections …

BACKGROUND: Inflammation contributes to all phases of the atherothrombotic process, and
patients with elevated inflammatory biomarkers such as high-sensitivity C-reactive protein …

There is compelling experimental and clinical evidence suggesting a crucial role for
inflammation in the initiation and also the progression of atherosclerosis. Numerous …

Interleukin-1 is a pro-inflammatory cytokine that has numerous biological effects, including
activation of many inflammatory processes (through activation of T cells, for example) …

The interleukin‐1 (IL‐1), IL‐18, and IL‐33 families of cytokines are related by mechanism of
origin, receptor structure, and signal transduction pathways utilized. All three cytokines are …

Insulin resistance is increasingly recognized as a chronic, low-level, inflammatory state.
Hyperinsulinemia and insulin action were initially proposed as the common preceding …

IL-1 is an important mediator of inflammation and tissue damage in multiple organs, both in
experimental animal models of disease and in human diseases. The IL-1 family consists of …

Hypertension as a multifactorial pathology is one of the most important cardiovascular risk
factors, affecting up to 30‐40% of the general population. Complex immune responses are …