Computational approaches to substrate-based cell motility

F Ziebert, IS Aranson - npj Computational Materials, 2016 - nature.com
Substrate-based crawling motility of eukaryotic cells is essential for many biological
functions, both in developing and mature organisms. Motility dysfunctions are involved in …

Motility and morphodynamics of confined cells

I Lavi, N Meunier, R Voituriez, J Casademunt - Physical Review E, 2020 - APS
We introduce a minimal hydrodynamic model of polarization, migration, and deformation of a
biological cell confined between two parallel surfaces. In our model, the cell is driven out of …

A Cahn--Hilliard Model for Cell Motility

A Cucchi, A Mellet, N Meunier - SIAM Journal on Mathematical Analysis, 2020 - SIAM
We introduce and study a diffuse interface model describing cell motility. We provide a
detailed rigorous analysis of the model in dimension 1 and formally derive the sharp …

Membrane tension feedback on shape and motility of eukaryotic cells

B Winkler, IS Aranson, F Ziebert - Physica D: Nonlinear Phenomena, 2016 - Elsevier
In the framework of a phase field model of a single cell crawling on a substrate, we
investigate how the properties of the cell membrane affect the shape and motility of the cell …

[PDF][PDF] Self polarization and traveling wave in a model for cell crawling migration

A Cucchi, A Mellet, N Meunier - Discrete and dynamical systems, 2022 - math.umd.edu
In this paper, we prove the existence of traveling wave solutions for an incompressible
Darcy's free boundary problem recently introduced in [6] to describe cell motility. This free …

On an obstacle problem for the Brakke flow with a generalized right-angle boundary condition

K Nik, K Takasao - SIAM Journal on Mathematical Analysis, 2025 - SIAM
We study Brakke's mean curvature flow with obstacles and with a right-angle boundary
condition. Assuming that the obstacles have-boundaries, we prove that a weak solution …

Bifurcation of finger-like structures in traveling waves of epithelial tissues spreading

L Berlyand, A Rybalko, V Rybalko… - Journal of Mathematical …, 2024 - Elsevier
We consider a continuous active polar fluid model for the spreading of epithelial monolayers
introduced by R. Alert, C. Blanch-Mercader, and J. Casademunt, 2019. The corresponding …

Phase-field model of cell motility: Traveling waves and sharp interface limit

L Berlyand, M Potomkin… - Comptes …, 2016 - comptes-rendus.academie-sciences …
L. Berlyand et al./CR Acad. Sci. Paris, Ser. I 354 (2016) 986–992 987 comme de brutales
mises en mouvement de la cellule et des oscillations de sa forme. Le modèle consiste en …

On obstacle problem for Brakke's mean curvature flow

K Takasao - SIAM Journal on Mathematical Analysis, 2021 - SIAM
We consider the obstacle problem of the weak solution to the mean curvature flow, in the
sense of Brakke's mean curvature flow. We prove the global existence of the weak solution …

[HTML][HTML] Gradient-descent-like scheme for the Allen–Cahn equation

D Lee - AIP Advances, 2023 - pubs.aip.org
The phase-field equations have many attractive characteristics. First, phase separation can
be induced by the phase-field equations. It transforms from a single homogeneous mixture …