Toolbox for distal C–H bond functionalizations in organic molecules

SK Sinha, S Guin, S Maiti, JP Biswas, S Porey… - Chemical …, 2021 - ACS Publications
Transition-metal-catalyzed C–H activation has developed a contemporary approach to the
omnipresent area of retrosynthetic disconnection. Scientific researchers have been tempted …

Strategies to generate nitrogen-centered radicals that may rely on photoredox catalysis: development in reaction methodology and applications in organic synthesis

K Kwon, RT Simons, M Nandakumar… - Chemical …, 2021 - ACS Publications
For more than 70 years, nitrogen-centered radicals have been recognized as potent
synthetic intermediates. This review is a survey designed for use by chemists engaged in …

Visible light photoredox-catalysed remote C–H functionalisation enabled by 1, 5-hydrogen atom transfer (1, 5-HAT)

W Guo, Q Wang, J Zhu - Chemical Society Reviews, 2021 - pubs.rsc.org
The generation of heteroatom-centred radicals (X˙), followed by intramolecular 1, 5-
hydrogen atom transfer (1, 5-HAT) and the functionalisation of the translocated carbon …

Visible light photocatalysis in the late-stage functionalization of pharmaceutically relevant compounds

R Cannalire, S Pelliccia, L Sancineto… - Chemical Society …, 2021 - pubs.rsc.org
The late stage functionalization (LSF) of complex biorelevant compounds is a powerful tool
to speed up the identification of structure–activity relationships (SARs) and to optimize …

Energy-transfer-induced [3+ 2] cycloadditions of N–N pyridinium ylides

W Lee, Y Koo, H Jung, S Chang, S Hong - Nature Chemistry, 2023 - nature.com
Photocycloaddition is a powerful reaction to enable the conversion of alkenes into high-
value synthetic materials that are normally difficult to obtain under thermal conditions …

Bifunctional reagents in organic synthesis

HM Huang, P Bellotti, J Ma, T Dalton… - Nature Reviews …, 2021 - nature.com
Developments in synthetic chemistry are increasingly driven by improvements in the
selectivity and sustainability of transformations. Bifunctional reagents, either as dual …

Site-selective direct C–H pyridylation of unactivated alkanes by triplet excited anthraquinone

W Lee, S Jung, M Kim, S Hong - Journal of the American Chemical …, 2021 - ACS Publications
Site-selective C–H functionalization in chemical feedstocks is a challenging and useful
reaction in the broad field of chemical research. Here, we report a modular photochemical …

Visible-light-driven C4-selective alkylation of pyridinium derivatives with alkyl bromides

S Jung, S Shin, S Park, S Hong - Journal of the American …, 2020 - ACS Publications
Reported herein is a general strategy for the photochemical cross-coupling between N-
amidopyridinium salts and various alkyl bromides under photocatalyst-free conditions …

N-Amino pyridinium salts in organic synthesis

P Roychowdhury, S Samanta, H Tan… - Organic Chemistry …, 2023 - pubs.rsc.org
C–N bond forming reactions hold immense significance to synthetic organic chemistry. In
pursuit of efficient methods for the introduction of nitrogen in organic small molecules …

Visible-light-induced metal-free coupling of C (sp 3)–H sources with heteroarenes

A Ghosh, P Pyne, S Ghosh, D Ghosh, S Majumder… - Green …, 2022 - pubs.rsc.org
Development of an efficient, mild, economically viable, and green method for the
construction of a Csp2–Csp3 bond via coupling between a saturated hydrocarbon [(Csp3) …