Circadian rhythms are internal manifestations of the solar day that permit adaptations to
predictable environmental temporal changes. These~ 24-h rhythms are controlled by …

Psychiatric disorders are among the most intractable enigmas in medicine. In the past 5
years, there has been unprecedented progress on the genetics of many of these conditions …

There is increasing evidence that genome-wide association (GWA) studies represent a
powerful approach to the identification of genes involved in common human diseases. We …

Background Whether schizophrenia and bipolar disorder are the clinical outcomes of
discrete or shared causative processes is much debated in psychiatry. We aimed to assess …

Behavioral Genetics, Fifth Edition provides an engaging and clear overview of human and
animal behavioral genetics that is designed to introduce students in the behavioral …

Our understanding of the molecular properties of kainate receptors and their involvement in
synaptic physiology has progressed significantly over the last 30 years. A plethora of studies …

Bipolar disorder is a mood disorder characterized by impairing episodes of mania and
depression. Twin studies have established that bipolar disorder is among the most heritable …

We performed a genome-wide association scan in 1461 patients with bipolar (BP) 1
disorder, 2008 controls drawn from the Systematic Treatment Enhancement Program for …

A concatenation of findings from preclinical and clinical studies support a preeminent
function for the corticotropin-releasing factor (CRF) system in mediating the physiological …

Several psychiatric disorders—such as bipolar disorder, schizophrenia and autism—are
highly heritable, yet identifying their genetic basis has been challenging, with most …