Flavonoids are a group of natural polyphenol substances abundant in vegetables, fruits,
grains, and tea. As plant secondary metabolites, flavonoids play essential roles in many …

In recent years, chronic overnutrition, such as consumption of a high-fat diet (HFD), has
been increasingly viewed as a significant modifiable risk factor for diseases such as …

Kaempferol, a flavonoid identified in a wide variety of dietary sources, has been reported to
possess anti-obesity properties; however, its underlying mechanism was poorly understood …

Type 2 diabetes (T2D) and obesity are relevant worldwide chronic diseases. A common
complication in both pathologies is the dysregulation of the insulin-signaling pathway that is …

Despite the early recognition of obesity as an epidemic with global implications, research on
its pathogenesis and therapeutic approach is still on the rise. The literature of the 21st …

Obesity is an increasing health concern related to many metabolic disorders, including
metabolic syndrome, diabetes type 2 and cardiovascular diseases. Many studies suggest …

The aim was to compare the antiobesity efficacy of different concentrations of a phenolic-rich
water extract from purple maize pericarp (PPE) in a murine model of obesity for 12 weeks …

Scientific research consistently demonstrates that diseases may be delayed, treated, or even
prevented and, thereby, health may be maintained with health-promoting functional food …

Cardiovascular diseases (CVDs) are among the leading causes of morbidity and mortality
worldwide. Unhealthy dietary habits have clearly been shown to contribute to the …

Microglia, a type of innate immune cell of the brain, regulates neurogenesis, immunological
surveillance, redox imbalance, cognitive and behavioral changes under normal and …