Acute kidney injury (AKI) is emerging as a complication of increasing clinical importance
associated with substantial morbidity and mortality in African children with severe malaria …

Background Chronic kidney disease (CKD) is a globally significant non-communicable
disorder. CKD prevalence varies between countries and within a country. We compared the …

This article is published as part of a supplement sponsored by Kidney Disease: Improving
Global Outcomes (KDIGO). The opinions or views expressed in this supplement are those of …

Rationale and Objective Glomerular filtration rate (GFR) estimation based on creatinine and
cystatin C (eGFR cr-cys) is more accurate than estimated GFR (eGFR) based on creatinine …

Background Chronic kidney disease (CKD) is a substantial cause of morbidity and mortality
worldwide with disproportionate effects in sub-Saharan Africa (SSA). The optimal methods to …

Background Use of race and ethnicity is common in medical tests and procedures, even
though these categories are defined by sociological, historical, and political processes, and …

Background Differences in serum creatinine concentration among groups defined by race
and ethnicity have been ascribed to differences in muscle mass. We examined differences in …

Genome-wide association studies (GWAS) of kidney function have uncovered hundreds of
loci, primarily in populations of European ancestry. We have undertaken the first continental …

Background The cause for differences in serum creatinine between Black and non-Black
individuals incorporated into prior GFR-estimating equations is not understood. We explored …

Background Acute kidney injury (AKI) is increasingly recognized as a consequential clinical
complication in children with severe malaria. However, approaches to estimate baseline …