Nuclear factor erythroid 2-related factor 2 (Nrf2) is a vital transcription factor and its induction
is of significant importance for protecting against oxidative damage. Increased levels of …

The transcription factor nuclear factor erythroid-derived 2-like 2 (NRF2) participates in the
activation of the antioxidant cytoprotective pathway and other important physiological …

The gene expression program induced by NRF2 transcription factor plays a critical role in
cell defense responses against a broad variety of cellular stresses, most importantly …

Breast cancer is the second leading cancer among all types of cancers. It accounts for 12%
of the total cases of cancers. The complex and heterogeneous nature of breast cancer …

Epigenetics has provided a new dimension to our understanding of nuclear factor erythroid
2–related factor 2/Kelch-like ECH-associated protein 1 (human NRF2/KEAP1 and murine …

AKR1B10 is a human nicotinamide adenine dinucleotide phosphate (NADPH)-dependent
reductase belonging to the aldo-keto reductase (AKR) 1B subfamily. It catalyzes the …

The MYH9 (Myosin heavy chain 9), an architecture component of the actomyosin
cytoskeleton, has been reported to be dysregulated in several types of cancers. However …

Background Lung squamous cell carcinoma (LUSC) currently has limited therapeutic
options because of the relatively few validated targets and the lack of clinical drugs for some …

The Nuclear factor erythroid 2-related factor 2 (Nrf2) protein has garnered significant interest
due to its crucial function in safeguarding cells and tissues. The Nrf2 protein is crucial in …

Wound healing (WH) and cancer seem to share common cellular and molecular processes
that could work in a tight balance to maintain tissue homeostasis or, when unregulated, drive …