Hyaluronic acid: redefining its role
G Abatangelo, V Vindigni, G Avruscio, L Pandis, P Brun - Cells, 2020 - mdpi.com
The discovery of several unexpected complex biological roles of hyaluronic acid (HA) has
promoted new research impetus for biologists and, the clinical interest in several fields of …
promoted new research impetus for biologists and, the clinical interest in several fields of …
Hyaluronan: molecular size‐dependent signaling and biological functions in inflammation and cancer
AG Tavianatou, I Caon, M Franchi… - The FEBS …, 2019 - Wiley Online Library
Hyaluronan (HA) is a linear nonsulfated glycosaminoglycan of the extracellular matrix that
plays a pivotal role in a variety of biological processes. High‐molecular weight HA exhibits …
plays a pivotal role in a variety of biological processes. High‐molecular weight HA exhibits …
[HTML][HTML] Development and application of hyaluronic acid in tumor targeting drug delivery
Z Luo, Y Dai, H Gao - Acta Pharmaceutica Sinica B, 2019 - Elsevier
Hyaluronic acid (HA) is a natural polysaccharide that has gained much attention due to its
biocompatibility, enzyme degradation capacity and active tumor targeting capacity. Its …
biocompatibility, enzyme degradation capacity and active tumor targeting capacity. Its …
Hyaluronic acid for anticancer drug and nucleic acid delivery
Hyaluronic acid (HA) is widely used in anticancer drug delivery, since it is biocompatible,
biodegradable, non-toxic, and non-immunogenic; moreover, HA receptors are …
biodegradable, non-toxic, and non-immunogenic; moreover, HA receptors are …
Ovarian Cancer Cell Line Panel (OCCP): Clinical Importance of In Vitro Morphological Subtypes
CM Beaufort, JCA Helmijr, AM Piskorz, M Hoogstraat… - PloS one, 2014 - journals.plos.org
Epithelial ovarian cancer is a highly heterogeneous disease and remains the most lethal
gynaecological malignancy in the Western world. Therapeutic approaches need to account …
gynaecological malignancy in the Western world. Therapeutic approaches need to account …
CD44: can a cancer-initiating cell profit from an abundantly expressed molecule?
M Zöller - Nature Reviews Cancer, 2011 - nature.com
Can an abundantly expressed molecule be a reliable marker for the cancer-initiating cells
(CICs; also known as cancer stem cells), which constitute the minority of cells within the …
(CICs; also known as cancer stem cells), which constitute the minority of cells within the …
Significance of CD44 and CD24 as cancer stem cell markers: an enduring ambiguity
A Jaggupilli, E Elkord - Journal of Immunology Research, 2012 - Wiley Online Library
Cancer stem cell population is a subset of cells capable of dictating invasion, metastasis,
heterogeneity, and therapeutic resistance in tumours. Eradication of this rare population is a …
heterogeneity, and therapeutic resistance in tumours. Eradication of this rare population is a …
Hyaluronic acid bioconjugates for the delivery of bioactive molecules
A Mero, M Campisi - Polymers, 2014 - mdpi.com
Hyaluronic acid (HA) has currently several therapeutic applications: in ophthalmology,
osteoarthritis, wound healing, tissue regeneration, postoperative anti-adhesion and …
osteoarthritis, wound healing, tissue regeneration, postoperative anti-adhesion and …
Advanced nanomedicine approaches applied for treatment of skin carcinoma
H Kaur, P Kesharwani - Journal of Controlled Release, 2021 - Elsevier
Skin-cancer is the commonest malignancy affecting huge proportion of the population,
reaching heights in terms of morbidity. The treatment strategies are presently focusing on …
reaching heights in terms of morbidity. The treatment strategies are presently focusing on …
Hyaluronate and its derivatives for customized biomedical applications
Since hyaluronate (HA) was firstly isolated from the vitreous of bovine eyes in 1934, HA has
been widely investigated for various biomedical applications. As a naturally-occurring …
been widely investigated for various biomedical applications. As a naturally-occurring …