Normal cells are hijacked by cancer cells forming together heterogeneous tumor masses
immersed in aberrant communication circuits that facilitate tumor growth and dissemination …

Abstract Forkhead box P3 (Foxp3) is an important transcription factor that belongs to the
forkhead/winged-helix family of transcriptional regulators. Foxp3 has been extensively …

Abstract The interleukin-10 (IL-10) is generally considered as the most important cytokine
with anti-inflammatory properties and one of the key cytokines preventing inflammation …

Gene therapy has become an important approach for treating cancer, and electroporation
represents a technology for introducing therapeutic genes into a cell. An example of cancer …

Human melanoma is one of the deadliest forms of cancer, with poor prognosis and high
resistance to chemotherapy and radiotherapy. The discovery of immunosuppressive …

Abstract Purpose Regulatory T cells (Tregs) impair the clinical benefit of cancer
immunotherapy. To optimize the antitumor efficacy of therapeutic dendritic cell (DC) …

Abstract Forkhead box protein 3 (FOXP3) transcription factor is expressed by immune cells
and several human cancers and is associated with tumor aggressiveness and unfavorable …

Immunosuppression in cancer poses challenges for immunotherapy and highlights the
vulnerability of immunocompromised patients to viral infections. This study explored how …

Background Recent research indicates a positive correlation between DEP structural
domain‐containing 1B (DEPDC1B) and the cell cycle in various tumors. However, the role of …

Biomarker discovery for early disease diagnosis is highly important. Of late, much effort has
been made to analyze complex biological fluids in an effort to develop new markers specific …