Primary prevention through lifestyle interventions is a cost-effective alternative for preventing
a large burden of chronic and degenerative diseases, including cancer, which is one of the …

Background In this review, we examine the continually expanding and increasingly
compelling data linking radiation and various chemicals in our environment to the current …

Diet and obesity are important risk factors for cancer development. Many studies have
suggested an important role for several dietary nutrients in the progression and …

Of any plant, soy contains the largest concentration of isoflavones, a class of
phytoestrogens. Phytoestrogens are structurally similar to estradiol and mimic its effects. Soy …

Background: Soy isoflavones have antiestrogenic and anticancer properties but also
possess estrogen-like properties, which has raised concern about soy food consumption …

Natural polyphenols are organic chemicals which contain phenol units in their structures.
They show antitumor properties. However, a key problem is their short half-life and low …

Primary and acquired resistance to the breast cancer drug trastuzumab (Herceptin) is a
significant clinical problem. Here, we report enhanced activation of downstream signaling …

Scientific achievements in the last two decades have revolutionized the treatment and
prevention of breast cancer. This is mainly because of targeted therapies and a better …

Many phytochemicals demonstrate nonmonotonic dose/concentration-response termed
biphasic dose-response and are considered to be hormetic compounds, ie, they induce …

In Asian epidemiological studies, health benefits, including reduced incidence of breast and
prostate cancers, are attributed to soy food and isoflavone consumption. The recent …