Systemic and ocular safety of intravitreal anti-VEGF therapies for ocular neovascular disease

M Tolentino - Survey of ophthalmology, 2011 - Elsevier
The treatment of ocular neovascular diseases is being revolutionized by intravitreal
therapies targeting vascular endothelial growth factor (VEGF). Two agents are approved for …

Submacular hemorrhage in neovascular age-related macular degeneration: a synthesis of the literature

D Stanescu-Segall, F Balta, TL Jackson - Survey of ophthalmology, 2016 - Elsevier
Large submacular hemorrhage, an uncommon manifestation of neovascular age-related
macular degeneration, may also occur with idiopathic polypoidal choroidal vasculopathy …

Naïve subretinal haemorrhage due to neovascular age-related macular degeneration. pneumatic displacement, subretinal air, and tissue plasminogen activator …

M Iglicki, M Khoury, JI Melamud, L Donato, A Barak… - Eye, 2023 - nature.com
Objective We aimed to compare visual and anatomical outcome in subretinal aflibercept vs.
intravitreal aflibercept in the context of Pars Plana Vitrectomy (PPV), pneumatic …

Comparison of sub retinal aflibercept vs ranibizumab vs bevacizumab in the context of PPV, pneu ma tic displacement with sub r etinal air and subret in al tPA in naïve …

M Iglicki, M Khoury, L Donato, DJ Quispe, HP Negri… - Eye, 2024 - nature.com
Objective To compare efficacy and safety profile of subretinal aflibercept, ranibizumab, and
bevacizumab in the context of pars plana vitrectomy, pneumatic displacement with …

Combined treatment of acute subretinal haemorrhages with intravitreal recombined tissue plasminogen activator, expansile gas and bevacizumab: a retrospective …

CH Meyer, HP Scholl, N Eter, HM Helb… - Acta …, 2008 - Wiley Online Library
Purpose: To assess the effectiveness of consecutive intravitreal injections of recombined
tissue plasminogen activator (rtPA), expansile gas and bevacizumab in eyes with acute …

Literature review of recombinant tissue plasminogen activator used for recent-onset submacular hemorrhage displacement in age-related macular degeneration

EJT Van Zeeburg, JC Van Meurs - Ophthalmologica, 2012 - karger.com
Aims: To review and discuss the literature on recombinant tissue plasminogen activator
(rtPA) for the treatment of a recent-onset submacular hemorrhage in patients with age …

Retinal and ocular toxicity in ocular application of drugs and chemicals–part II: retinal toxicity of current and new drugs

FM Penha, EB Rodrigues, M Maia, BA Furlani… - Ophthalmic …, 2010 - karger.com
Aims: Retinal pharmacotherapy has gained great importance for the treatment of various
retinal diseases. An increasing number of drugs have been constantly released into the …

Neuroprotective effect of intravitreal triamcinolone acetonide against photoreceptor apoptosis in a rabbit model of subretinal hemorrhage

RB Bhisitkul, BJ Winn, OT Lee, J Wong… - … & visual science, 2008 - iovs.arvojournals.org
purpose. To study photoreceptor apoptosis and iron migration as mechanisms of
retinotoxicity in a rabbit model of subretinal hemorrhage (SRH) and to assess intravitreal …

Subretinal coapplication of recombinant tissue plasminogen activator and bevacizumab for neovascular age-related macular degeneration with submacular …

F Treumer, C Klatt, J Roider… - British Journal of …, 2010 - bjo.bmj.com
Aim: To evaluate the efficacy and safety of pars plana vitrectomy (ppV) with subretinal
coapplication of recombinant tissue plasminogen activator (rtPA) and bevacizumab, and …

Submacular haemorrhages associated with neovascular age-related macular degeneration

DHW Steel, SS Sandhu - British journal of ophthalmology, 2011 - bjo.bmj.com
The exact incidence of submacular haemorrhage (SMH) in patients with neovascular age-
related macular degeneration (nAMD) is unknown, and risk factors for its occurrence ill …