Ocular drug delivery: present innovations and future challenges
Ocular drug delivery has always been a challenge for ophthalmologists and drug-delivery
scientists due to the presence of various anatomic and physiologic barriers. Inimitable static …
scientists due to the presence of various anatomic and physiologic barriers. Inimitable static …
Phytochemistry, pharmacological activity, and potential health benefits of Glycyrrhiza glabra
Nature has always been an excellent source for many therapeutic compounds providing us
with many medicinal plants and microorganisms producing beneficial chemicals. Therefore …
with many medicinal plants and microorganisms producing beneficial chemicals. Therefore …
Polymeric micelles for ocular drug delivery: From structural frameworks to recent preclinical studies
Effective intraocular drug delivery poses a major challenge due to the presence of various
elimination mechanisms and physiological barriers that result in low ocular bioavailability …
elimination mechanisms and physiological barriers that result in low ocular bioavailability …
Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery
Eye diseases and injuries impose a significant clinical problem worldwide. Safe and
effective ocular drug delivery is, however, challenging due to the presence of ocular barriers …
effective ocular drug delivery is, however, challenging due to the presence of ocular barriers …
BCLA CLEAR-Contact lens complications
Contact lens-related complications are common, affecting around one third of wearers,
although most are mild and easily managed. Contact lenses have well-defined anatomical …
although most are mild and easily managed. Contact lenses have well-defined anatomical …
Vascular endothelial growth factor signaling in hypoxia and inflammation
Infection, cancer and cardiovascular diseases are the major causes for morbidity and
mortality in the United States according to the Center for Disease Control. The underlying …
mortality in the United States according to the Center for Disease Control. The underlying …
Clinical pharmacology of intravitreal anti-VEGF drugs
Clinical efficacy of intravitreal anti-VEGF drugs has been widely demonstrated in several
angiogenesis-driven eye diseases including diabetic macular edema and the neovascular …
angiogenesis-driven eye diseases including diabetic macular edema and the neovascular …
Ocular delivery of proteins and peptides: Challenges and novel formulation approaches
The impact of proteins and peptides on the treatment of various conditions including ocular
diseases over the past few decades has been advanced by substantial breakthroughs in …
diseases over the past few decades has been advanced by substantial breakthroughs in …
Therapeutic potentials of gene silencing by RNA interference: principles, challenges, and new strategies
Y Deng, CC Wang, KW Choy, Q Du, J Chen, Q Wang… - Gene, 2014 - Elsevier
During recent decades there have been remarkable advances in biology, in which one of
the most important discoveries is RNA interference (RNAi). RNAi is a specific post …
the most important discoveries is RNA interference (RNAi). RNAi is a specific post …
Biodegradable silicon nanoneedles for ocular drug delivery
Ocular drug delivery remains a grand challenge due to the complex structure of the eye.
Here, we introduce a unique platform of ocular drug delivery through the integration of …
Here, we introduce a unique platform of ocular drug delivery through the integration of …