HIV-1 drug resistance and resistance testing
DS Clutter, MR Jordan, S Bertagnolio… - Infection, Genetics and …, 2016 - Elsevier
The global scale-up of antiretroviral (ARV) therapy (ART) has led to dramatic reductions in
HIV-1 mortality and incidence. However, HIV drug resistance (HIVDR) poses a potential …
HIV-1 mortality and incidence. However, HIV drug resistance (HIVDR) poses a potential …
Drug resistance mutations in HIV: new bioinformatics approaches and challenges
Highlights•Machine learning is increasingly used to predict and understand drug resistance
in HIV.•Phylogenetics helps to track the emergence and spread of HIV drug resistance …
in HIV.•Phylogenetics helps to track the emergence and spread of HIV drug resistance …
Transmission network parameters estimated from HIV sequences for a nationwide epidemic
Background. Many studies of sexual behavior have shown that individuals vary greatly in
their number of sexual partners over time, but it has proved difficult to obtain parameter …
their number of sexual partners over time, but it has proved difficult to obtain parameter …
Molecular epidemiology reveals long-term changes in HIV type 1 subtype B transmission in Switzerland
Background. Sequence data from resistance testing offer unique opportunities to
characterize the structure of human immunodeficiency virus (HIV) infection epidemics …
characterize the structure of human immunodeficiency virus (HIV) infection epidemics …
[PDF][PDF] European recommendations for the clinical use of HIV drug resistance testing: 2011 update
AM Vandamme, RJ Camacho, F Ceccherini-Silberstein… - Aids Rev, 2011 - academia.edu
Abstract The European HIV Drug Resistance Guidelines Panel, established to make
recommendations to clinicians and virologists, felt that sufficient new information has …
recommendations to clinicians and virologists, felt that sufficient new information has …
HIV-1 transmission during early infection in men who have sex with men: a phylodynamic analysis
Background Conventional epidemiological surveillance of infectious diseases is focused on
characterization of incident infections and estimation of the number of prevalent infections …
characterization of incident infections and estimation of the number of prevalent infections …
Characterizing HIV transmission networks across the United States
Background. Clinically, human immunodeficiency virus type 1 (HIV-1) pol sequences are
used to evaluate for drug resistance. These data can also be used to evaluate transmission …
used to evaluate for drug resistance. These data can also be used to evaluate transmission …
A novel methodology for large-scale phylogeny partition
Understanding the determinants of virus transmission is a fundamental step for effective
design of screening and intervention strategies to control viral epidemics. Phylogenetic …
design of screening and intervention strategies to control viral epidemics. Phylogenetic …
Phylogenetic studies of transmission dynamics in generalized HIV epidemics: an essential tool where the burden is greatest?
AM Dennis, JT Herbeck, AL Brown… - JAIDS Journal of …, 2014 - journals.lww.com
Efficient and effective HIV prevention measures for generalized epidemics in sub-Saharan
Africa have not yet been validated at the population level. Design and impact evaluation of …
Africa have not yet been validated at the population level. Design and impact evaluation of …
Simple epidemiological dynamics explain phylogenetic clustering of HIV from patients with recent infection
Phylogenies of highly genetically variable viruses such as HIV-1 are potentially informative
of epidemiological dynamics. Several studies have demonstrated the presence of clusters of …
of epidemiological dynamics. Several studies have demonstrated the presence of clusters of …