[HTML][HTML] Copper (II) phenanthroline-based complexes as potential anticancer drugs: a walkthrough on the mechanisms of action
Copper is an endogenous metal ion that has been studied to prepare a new antitumoral
agent with less side-effects. Copper is involved as a cofactor in several enzymes, in ROS …
agent with less side-effects. Copper is involved as a cofactor in several enzymes, in ROS …
Mixed ligand copper (II)-diimine complexes of 2-formylpyridine-N 4-phenylthiosemicarbazone: Diimine co-ligands tune the in vitro nanomolar cytotoxicity
R Kartikeyan, D Murugan, T Ajaykamal… - Dalton …, 2023 - pubs.rsc.org
Recently, mixed-ligand copper (II) complexes have received much attention in searching for
alternative metallodrugs to cisplatin. A series of mixed ligand Cu (II) complexes of the type …
alternative metallodrugs to cisplatin. A series of mixed ligand Cu (II) complexes of the type …
Cytotoxic mixed-ligand copper (ii) complexes with 1 H-tetrazole-5-acetic acid and oligopyridine derivatives
EA Ermakova, YA Golubeva, KS Smirnova… - New Journal of …, 2023 - pubs.rsc.org
Herein, we present the synthesis, characterization, and in vitro investigation of cytotoxic
activity against cancer (HepG-2, MCF-7) and non-cancerous (Hek-293, MRC-5) cell lines of …
activity against cancer (HepG-2, MCF-7) and non-cancerous (Hek-293, MRC-5) cell lines of …
Mixed-ligand copper (ii)-diimine complexes of 3-formylchromone-N 4-phenyl thiosemicarbazone: 5, 6-dmp co-ligand confers enhanced cytotoxicity
The promising biological applications of thiosemicarbazone derivatives have inspired the
design, synthesis, and study of their Cu (II) complexes for anticancer therapeutic …
design, synthesis, and study of their Cu (II) complexes for anticancer therapeutic …
Comparative DNA-/BSA-binding, DNA cleavage, and cytotoxic properties of copper (II) amino/salicyl-phenolate Schiff bases (phen) complexes that induce generation …
A Mamindla, M Varadhan, R Kartikeyan… - Polyhedron, 2023 - Elsevier
A series of mixed-ligand Cu (II) complexes of the type [Cu (L 1-5)(diimine)(H 2 O)](ClO 4)(1–
5) and [Cu (L 6)(diimine)](ClO 4)(6), where HL 1-HL 4 are aminophenolate Schiff base …
5) and [Cu (L 6)(diimine)](ClO 4)(6), where HL 1-HL 4 are aminophenolate Schiff base …
Novel Ru (II)-bipyridine/phenanthroline-lapachol complexes as potential anti-cancer agents
RA De Grandis, AR Costa, CAF Moraes… - Journal of Inorganic …, 2022 - Elsevier
For the first time, we herein report on the syntheses of two new Ru (II)/bipyridine/
phenanthroline complexes containing lapachol as ligand: complex (1),[Ru (bipy) 2 (Lap)] PF …
phenanthroline complexes containing lapachol as ligand: complex (1),[Ru (bipy) 2 (Lap)] PF …
Folic acid-conjugated mixed-ligand copper (II) complexes as promising cytotoxic agents for triple-negative breast cancers: A case study using MDA-MB-231 cell
S Karpagam, A Mamindla, VK Sali, RS Niranjana… - Inorganica Chimica …, 2022 - Elsevier
The new mixed-ligand copper (II) complexes [Cu (FAA)(diimine)(H 2 O)](ClO 4) 2 (1–4)[FAA
is folic acid-conjugated ethyl pyridyl amine; diimine is 1, 10-phenanthroline (phen; 1), 5, 6 …
is folic acid-conjugated ethyl pyridyl amine; diimine is 1, 10-phenanthroline (phen; 1), 5, 6 …
5-Hydroxyisophthalic acid and neocuproine containing copper (II) complex as a promising cytotoxic agent: Structure elucidation, topology, Hirshfeld surface, DFT …
We aimed to synthesize a new copper (II) complex, namely [Cu (H 2 IPA)(NC)(Cl)]⋅ H 2 O
(1)(where, H 3 IPA= 5-hydroxy isophthalic acid and NC= 2, 9-dimethyl-1, 10-phenanthroline …
(1)(where, H 3 IPA= 5-hydroxy isophthalic acid and NC= 2, 9-dimethyl-1, 10-phenanthroline …
Cytotoxic Copper(II) Complexes Based on 2,2'-Bipyridine/1,10-Phenanthroline and 5-(4-Chlorophenyl)-1H-tetrazole: Synthesis and Structures
YA Golubeva, KS Smirnova, LS Klyushova… - Russian Journal of …, 2023 - Springer
Abstract Five coordination compounds [Cu2 (Bipy) 2L4]· C2H5OH (Iа, Ib),[Cu2 (Dmbipy)
2L4](II),[Cu2 (Phen) 2L4]· H2O (IIIa),[Cu2 (Dmphen) 2L4](IVa), and [Cu2 (Phendione') 2L4] …
2L4](II),[Cu2 (Phen) 2L4]· H2O (IIIa),[Cu2 (Dmphen) 2L4](IVa), and [Cu2 (Phendione') 2L4] …