Synaptic vesicle recycling is one of the best‐studied cellular pathways. Many of the proteins
involved are known, and their interactions are becoming increasingly clear. However, as for …

Neurotransmission in complex animals depends on a choir of functionally distinct synapses
releasing neurotransmitters in a highly coordinated manner. During synaptic signaling …

Synaptic communication in the nervous system is initiated by the fusion of synaptic vesicles
with the presynaptic plasma membrane and subsequent neurotransmitter release. In the …

Alpha-synuclein (α-syn) has gained significant attention due to its involvement in
neurodegenerative diseases, particularly Parkinson's disease. However, its normal function …

Cognitive-motivational styles describe predominant patterns of processing or biases that
broadly influence human cognition and performance. Here we focus on the impact of …

Synaptic vesicles are tethered to the active zone where they are docked/primed so that they
can fuse rapidly upon Ca 2+ influx. To directly study these steps at a CNS presynaptic …

The calyx of Held synapse plays an important role in the auditory system, relaying
information about sound localization via fast and precise synaptic transmission, which is …

A rise in the occurrence of obesity has driven exploration of its underlying genetic basis and
potential targets for intervention. GWAS studies have identified obesity susceptibility …

Although vesicle replenishment is critical in maintaining exo-endocytosis recycling, the
underlying mechanisms are not well understood. Previous studies have shown that both …

Vesicle recycling is pivotal for maintaining reliable synaptic signaling, but its basic properties
remain poorly understood. Here, we developed an approach to quantitatively analyze the …