Epithelial cells repress epithelial characteristics and elaborate mesenchymal characteristics
to migrate to other locations and acquire new properties. Epithelial plasticity responses are …

Most research on mechanisms of aging is being conducted in a very limited number of
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …

Hydra's almost unlimited regenerative potential is based on Wnt signaling, but so far it is
unknown how the injury stimulus is transmitted to discrete patterning fates in head and foot …

In animals, stem cell populations of varying potency facilitate regeneration and tissue
homeostasis. Notably, germline stem cells in both vertebrates and invertebrates express …

Cnidarians are> 600 million years old and are considered the sister group of Bilateria based
on numerous molecular phylogenetic studies. Apart from Hydra, the genomes of all major …

The extent of tissue regeneration varies widely between species. Mammals have a limited
regenerative capacity whilst lower vertebrates such as the zebrafish (Danio rerio), a …

Morphological regeneration is an important feature that highlights the environmental
adaptive capacity of biological systems. Lack of this regenerative capacity significantly limits …

Which genes and gene signaling pathways mediate regenerative processes? In recent
years, multiple studies, using a variety of animal models, have aimed to answer this …

Mechanical input shapes cell fate decisions during development and regeneration in many
systems, yet the mechanisms of this cross-talk are often unclear. In regenerating Hydra …

The capacity to regenerate lost or injured body parts is a widespread feature within
metazoans and has intrigued scientists for centuries. One of the most extreme types of …