[HTML][HTML] Behind every smile there's teeth: Cathepsin B's function in health and disease with a kidney view
M Saudenova, J Promnitz, G Ohrenschall… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Cathepsin B (CatB) is a very abundant lysosomal protease with endo-and
carboxydipeptidase activities and even ligase features. In this review, we will provide a …
carboxydipeptidase activities and even ligase features. In this review, we will provide a …
Chaperone-Mediated Autophagy in Brain Injury: A Double-Edged Sword with Therapeutic Potentials
H Zhang, Y Tian, S Ma, Y Ji, Z Wang, P Xiao… - Molecular …, 2024 - Springer
Autophagy is an intracellular recycling process that maintains cellular homeostasis by
degrading excess or defective macromolecules and organelles. Chaperone-mediated …
degrading excess or defective macromolecules and organelles. Chaperone-mediated …
TMEM175 downregulation participates in impairment of the autophagy related lysosomal dynamics following neonatal hypoxic‐ischemic brain injury
H Zhang, Y Tian, W Yu, D Tong, Y Ji… - Journal of Cellular …, 2023 - Wiley Online Library
The mechanism underlying long‐term cognitive impairment caused by neonatal hypoxic‐
ischemic brain injury (HIBI) remains unclear. Autophagy is a closely related mechanism and …
ischemic brain injury (HIBI) remains unclear. Autophagy is a closely related mechanism and …
Cathepsin B knockout confers significant brain protection in the mouse model of stroke
Background Significant advances have been made in our understanding of the
endolysosomal cycle. Disruption of this cycle leads to cell death. The objective of this study …
endolysosomal cycle. Disruption of this cycle leads to cell death. The objective of this study …
The critical role of the endolysosomal system in cerebral ischemia
HY Zhang, Y Tian, HY Shi, Y Cai… - Neural Regeneration …, 2023 - journals.lww.com
Cerebral ischemia is a serious disease that triggers sequential pathological mechanisms,
leading to significant morbidity and mortality. Although most studies to date have typically …
leading to significant morbidity and mortality. Although most studies to date have typically …
丁酸钠对氟中毒模型大鼠的神经保护及乙酰化蛋白组学分析
李洋杰， 祁荣， 张馨予， 程佳佶， 周柠， 崔雪， 程双… - 中国组织工程研究, 2023 - cjter.com
丁酸钠对氟中毒模型大鼠的神经保护及乙酰化蛋白组学分析 Page 1 Chinese Journal of Tissue
Engineering Research|Vol 27|No.20|July 2023|3151 中国组织工程研究 Chinese Journal of …
Engineering Research|Vol 27|No.20|July 2023|3151 中国组织工程研究 Chinese Journal of …
Changes in early endosomes in rat hippocampal CA1 neurons after transient global cerebral ischaemia
M Qiang, BH Tan, DS Huo, SL Li… - Folia Histochemica …, 2024 - journals.viamedica.pl
Introduction. Transient global ischaemia in rodents causes selective loss of hippocampal
CA1neurons, but the potential involvement of endocytic pathways has not been fully …
CA1neurons, but the potential involvement of endocytic pathways has not been fully …
内溶酶体系统在脑缺血中的关键作用
HY Zhang, Y Tian, HY Shi, Y Cai, Y Xu - 中国神经再生研究(英文版), 2023 - sjzsyj.com.cn
脑缺血是一种引发连续病理机制的严重疾病, 导致显著的发病率和死亡率.
以往大部分关于在脑缺血发病机制的研究只提及了溶酶体是单一细胞器, 但最新研究表明 …
以往大部分关于在脑缺血发病机制的研究只提及了溶酶体是单一细胞器, 但最新研究表明 …
Neuroprotective effects of sodium butyrate and acetylation proteomics analysis in fluorosis rats
Y Li, R Qi, X Zhang, J Cheng, N Zhou, X Cui… - Chinese Journal of …, 2023 - cjter.com
BACKGROUND: Acetylation, one of the post-translational modifications of proteins, can
induce changes in gene expression related to synaptic connection and memory storage by …
induce changes in gene expression related to synaptic connection and memory storage by …